Kefzol Injection 1 gm 1 Vial works by interfering with the bacterial cell wall synthesis.
Side effects
Major & minor side effects for Kefzol Injection 1 gm 1 Vial

Diarrhea

Pain at injection site

Loss of appetite

Dizziness and Drowsiness rare

Swelling of legs and feet severe

Fainting severe

Skin Rash rare

Uses of Kefzol Injection 1 gm 1 Vial
What is it prescribed for?

Endocarditis
Kefzol Injection 1 gm 1 Vialis used in the treatment of endocarditis caused by Staphylococcus aureus, Streptococcus pyogenes, or group A beta-hemolytic streptococci.

Urinary tract infection
This medicine is used in the treatment of acute, uncomplicated urinary tract infections caused by E. coli, Proteus mirabilis, Klebsiella species, etc.

Cholecystitis
This medicine is used to treat cholecystits, a condition characterized by right upper abdominal pain, nausea, vomiting, and fever.

Surgical prophylaxis
This medicine may be used before, during, and after surgical procedures to prevent infections.

Skin and Skin Structure Infection
This medicine is used in the treatment of skin infections caused by Staphylococcus aureus, Streptococcus pyogenes, group A beta-hemolytic streptococci, etc.

Bone and Joint infections
This medicine is used in the treatment of bone and joint infections caused by Staphylococcus aureus.

Genital Infections
This medicine is used in the treatment of genital infections such as prostatitis and epididymitis caused by E. coli, Proteus mirabilis, Klebsiella species, etc.

Respiratory Tract Infection
This medicine is used in the treatment of respiratory tract infections caused by Staphylococcus aureus, Streptococcus pyogenes, group A beta-hemolytic streptococci, Klebsiella species, and Haemophilus influenzae.

Concerns

Frequently asked questions

Onset of action
The amount of time required for this medicine to show its action is 1 to 2 hours.

Duration of Effect
The time until which this medicine remains active in the body is 6 to 12 hours.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendency has been reported.

Usage in pregnancy?
This medicine is recommended for use in pregnant women only if necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

Usage while breast-feeding?
This medicine is considered safe for use in breastfeeding women. However, the infant should be monitored closely for any side effects such as diarrhea or thrush.

When not to use?

Hypersensitivity
This medicine is not recommended for use in patients with a known allergy to Kefzol Injection 1 gm 1 Vial or any other cephalosporins.

Warnings

Warnings for special population

Pregnancy
This medicine is recommended for use in pregnant women only if necessary. Discuss all the risks and benefits with your doctor before receiving this medicine.

Breast-feeding
This medicine is considered safe for use in breastfeeding women. However, the infant should be monitored closely for any side effects such as diarrhea or thrush.

General Warnings

Seizure disorder
This medicine should be used with extreme caution in patients with a known history of seizure disorder due to the increased risk of worsening of the patient’s condition. If a seizure episode occurs, therapy with this medicine should be discontinued and appropriate corrective measures should be taken.

Clostridium difficile-associated Diarrhea
Clostridium difficile-associated Diarrhea

Drug resistance
Usage of Kefzol Injection 1 gm 1 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Dosage

Missed Dose
Since this medicine is taken under the supervision of a qualified healthcare professional, usually in the clinical or hospital setup, the likelihood of missing a dose is very less.

Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Warfarin moderate

Furosemide moderate

Probenecid moderate

Disease interactions

severe
This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects on the kidney. This risk is especially higher in the elderly population. Close monitoring of kidney function is recommended during treatment with this medicine. Appropriate dose adjustments should be done based on the severity of renal dysfunction. Any unusual symptoms should be reported to the doctor on priority.

moderate
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe side effects. Close monitoring of liver function is recommended during treatment with this medicine. Any unusual symptoms should be reported to the doctor on priority.

General Instructions

This medicine should be taken under the supervision of a qualified healthcare professional. Report any unusual symptoms to the doctor immediately. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

References

practo.com –
Cefazolin [Internet].
Available from: https://www.practo.com/medicine-info/cefazolin-662-api
[cited 17 september 2019].
15 Aug 2017

drugbank.ca –
Cefazolin [Internet].
Available from: https://www.drugbank.ca/drugs/DB01327
[cited 17 september 2019].
September 29, 2019

medlineplus.gov –
Cefazolin Injection [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a682731.html
[cited 17 september 2019].
11 September 2019