Description

?-Conotoxin IMI is a peptide inhibitor of ?7 nicotinic acetylcholine receptors (nAChRs) originally found in species of Conus snails. ?-Conotoxin IMI disrupts motor coordination, inhibiting the swimming ability of leeches. Like other conotoxins, ?-conotoxin IMI binds the interface between different subunits of nAChRs.