Cabazitaxel

in Analytical
Sku: 1762985939-2434
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₦580,210.00

Product Info Cas No. 183133-96-2 Purity ?98% Formula C45H57NO14 Formula Wt. 835.94 Chemical Name 1-hydroxy-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-ene-2,4,13-triyl 4-acetate 2-benzoate 13-((2R,3S)-3-(((tertbutoxy)carbonyl)amino)-2-hydroxy-3-phenylpropanoate) IUPAC Name (2?,5?,7?,10?,13?)-4-Acetoxy-1-hydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate Synonym XPR-6258, TXD 258, Taxoid XRP6258, RPR 116258A, jevtana. Solubility Soluble in DMSO (~100 mg/mL), ethanol (~50 mg/mL). Sparingly soluble in water.
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Description

Cabazitaxel is a semi-synthetic taxoid that is an effective antineoplastic agent used in the treatment of prostate cancer and breast cancer. Cabazitaxel is shown to disrupt the microtubular network in cells that exhibit P-glycoprotein (Pgp) mediated drug resistance. Its poor affinity for Pgp makes it a more effective therapeutic agent than docetaxel in cancer cells that become resistant to the taxane class of cancer drugs.

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