Brivudine

Name: Brivudine
SKU: 1762986071-2472
Availability: InStock

in Analytical

Sku: 1762986071-2472

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Features

Product Info Cas No. 69304-47-8 Purity ?98% Formula C11H13BrN2O5 Formula Wt. 333.13 Chemical Name 5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione IUPAC Name 5-[(E)-2-bromoethenyl]-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione Melting Point 165?C Appearance White Crystal Powder

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Description

Description

Brivudine is a L-nucleoside analog of thymidine that exhibits antiviral, anticancer chemotherapeutic, and insecticidal activities. Brivudine inhibits herpes simplex virus (HSV-1) thymidine kinase, preventing DNA chain elongation and inhibiting viral growth. Brivudine also binds heat shock protein 27 (HSP27/HSPB1), improving the efficacy of co-administered chemotherapeutics in vivo and in clinical settings. This compound also exhibits properties of an insecticide, slowing larval growth and development of Spodoptera worms.

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