Alfuzosin is a prescription medication. It?s available as an oral extended-release tablet. Alfuzosin is available as the brand-name drug Uroxatral. It?s also available in a generic version. Alfuzosin belongs to a class of drugs called alpha-blockers. It works by helping to relax muscles in your prostate and bladder. This can reduce your BPH symptoms and improve your ability to urinate.