CAY10502 – 98%, high purity , CAS No.888320-29-4, Inhibitor of cPLA 2-4A

Name: CAY10502 - 98%, high purity , CAS No.888320-29-4, Inhibitor of cPLA 2-4A
SKU: 1759791498-1383
Price: 534465.00 NGN
Availability: InStock

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Sku: 1759791498-1383

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Features

Pubchem Sid504766635 Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504766635 Canonical SmilesCCCCCCCCCCOC1=CC=C(C=C1)OCC(=O)CN2C=C(C3=C2C=CC(=C3)C(=O)O)C(=O)OC IUPAC Name1-[3-(4-decoxyphenoxy)-2-oxopropyl]-3-methoxycarbonylindole-5-carboxylic acid InChIKeyNXDZVUAKVFVDSL-UHFFFAOYSA-N INCHI1S/C30H37NO7/c1-3-4-5-6-7-8-9-10-17-37-24-12-14-25(15-13-24)38-21-23(32)19-31-20-27(30(35)36-2)26-18-22(29(33)34)11-16-28(26)31/h11-16,18,20H,3-10,17,19,21H2,1-2H3,(H,33,34) Isomeric SMILES CCCCCCCCCCOC1=CC=C(C=C1)OCC(=O)CN2C=C(C3=C2C=CC(=C3)C(=O)O)C(=O)OC Alternate CAS 888320-29-4 Molecular Weight 523.62 Reaxy-Rn 10620712 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10620712&ln=

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Description

Description

CAY10502 is a potent Calcium-dependent cytosolic PLA2 (cPLA2?) inhibitor with an IC50 value of 4.3 nM for the purified enzyme from human platelets. Inhibits arachidonic acid mobilization from A23187-stimulated or TPA-stimulated human platelets with IC50 values of 570 and 0.9 nM, respectively.

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