10-Deacetyltaxol

in Analytical
Sku: 1762988340-3046
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Product Info Cas No. 78432-77-6 Purity ?98% Formula C45H49NO13 Formula Wt. 811.87 IUPAC Name [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate Synonym 10-Deacetylpaclitaxel, Deacetyltaxol, 10-Desacetyl Paclitaxel, 10-Deacetylpaclitaxel Solubility Soluble in organic solvents. Appearance White Powder
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Description

10-Deacetyltaxol is a taxane found in Taxus that exhibits nephroprotective and anticancer activities. Like other taxanes, this compound binds tubulin and promotes microtubule assembly, preventing depolymerization. In animal models of polycystic kidney disease, 10-deacetyltaxol inhibits disease progression. This compound also inhibits growth of cervical carcinoma cells, glioblastoma cells, and neuroblastoma cells.

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