1,4-DPCA

in Analytical
Sku: 1762988358-3052
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Product Info Cas No. 331830-20-7 Purity ?98% Formula C13H8N2O3 Formula Wt. 240.22 Chemical Name 4,4alpha-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid IUPAC Name 4-Hydroxy-1,10-phenanthroline-3-carboxylic acid Synonym 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid, 3-Acetyl-1H-[1,10]phenanthrolin-4-one Solubility Soluble in: DMSO (2.5 mg/mL, warm); ethanol (5 mg/mL, warm); DMF (5 mg/mL) Appearance Tan Powder
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Description

1,4-DPCA is an inhibitor of prolyl hydroxylase that stabilizes expression of HIF-1? and exhibits anticancer and pro-angiogenic activities. In breast cancer cells, 1,4-DPCA inhibits cell proliferation and decreases deposition of collagens I and IV. This compound also limits growth of connective tissue on biomaterials and implanted medical devices.

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