17-?-Ethynylestradiol

in Analytical
Sku: 1762988276-3025
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Product Info Cas No. 57-63-6, 77538-56-8, 406932-93-2, 1050678-65-3 Purity ?99% Formula C20H24O2 Formula Wt. 296.40 Chemical Name (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol IUPAC Name (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol Synonym Ethinylestradiol Melting Point 182-183?C Appearance White to off white powder
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Description

17-?-ethynylestradiol is a synthetic estrogen receptor (ER) agonist clinically used in contraceptive medications. In pregnant rats, 17-?-ethynylestradiol decreases platelet activating factor acetylhydrolase activity, inducing premature birth. 17-?-ethynylestradiol also displays weak antioxidative activity in lipid peroxidation assays in liver microsomes. Both acute and chronic exposure of wildlife (particularly fish) to 17-?-ethynylestradiol leads to feminization of males (through the induction of vitellogenin production), inhibiting fertility.

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