Description

2?,3?-Dideoxyinosine is a purine (guanosine) nucleoside analog that exhibits antiviral activity through the direct inhibition of reverse transcriptase. 2?,3?-Dideoxyinosine acts as a chain terminator and is one component of highly active antiretroviral therapy (HAART) regimens used in the treatment of HIV and AIDS. 2?,3?-Dideoxyinosine also inhibits the humoral immune response in vivo, targeting B lymphocytes.