A-Calm50 mg

A-Calm 50 mgA-Calm 50 mg is indicated in- Treatment of increased tone of skeletal muscles due to organic neurological disorders (injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis). Treatment of muscular spasm, muscular contracture, rigidity, spinal automatism. ... Read moreA-Calm 50 mg is indicated in- Treatment of increased tone of skeletal muscles due to organic neurological disorders (injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis). Treatment of muscular spasm, muscular contracture, rigidity, spinal automatism. In the treatment of vascular diseases (Obliterative arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, Raynaud's disease, diffuse scleroderma). In individual cases, post-thrombotic venous and lymphatic circulation disorders and crural ulcer. Theropeutic ClassCentral Depolarizing muscle relaxants, Centrally acting Skeletal Muscle RelaxantsPharmacologyTolperisone is a centrally acting muscle relaxant that acts at the reticular formation in the brain stem by blocking voltage-gated sodium and calcium channelsDosage & Administration of A-Calm 50 mgAdult: 150-450 mg daily, administered in 2 or 3 divided doses. The maximum dosage is 450 mg/day.Children: 3 months to 6 years: 1-2 mg/kg/day in 3 divided doses. 6 years to 14 years: 2-4 mg/kg/day in 3 divided doses Dosage of A-Calm 50 mgThe recommended dose is as follows: Adult: 50-150 mg three times daily according to the individual requirement and tolerance of the patient. Children (from 3 months to 6 years): 5 mg/kg/day in three divided doses. Children (from 6 to 14 years): 2-4 mg/kg/day in three divided doses. or, as directed by the registered physician. Interaction of A-Calm 50 mgConcomitant use of methocarbamol with A-Calm 50 mg has been reported to cause disturbance of visual accommodation.ContraindicationsIt is contraindicated in patients with a history of hypersensitivity to any component of the product, myasthenia gravis and nursing mother.Side Effects of A-Calm 50 mgPossible side-effects include sometimes muscular weakness, headache, nausea, vomiting and rarely hypersensitivity reactions (itching, redness of the skin, skin rash) may occur.Pregnancy & LactationA-Calm 50 mg should be used in pregnancy according to physician's advice. Tolperisone hydrochloride should not be used during breast-feeding.Precautions & WarningsIn case of children, the prescribed dose and duration of treatment should closely be observed.Overdose Effects of A-Calm 50 mgExcitability has been noted after ingestion of high doses by children. In suicide studies of three isolated cases, it is believed that ingestion of tolperisone was the cause of death.Storage ConditionsKeep below 30?C temperature, away from light & moisture. Keep out of the reach of children.Drug ClassesCentral Depolarizing muscle relaxants, Centrally acting Skeletal Muscle RelaxantsMode Of ActionA-Calm 50 mg is a centrally acting muscle relaxant, which acts on the central nervous system and used mainly for the treatment of elevated muscle tone and tension as well as for certain circulation problems in the extremities.PregnancyA-Calm 50 mg should be used in pregnancy according to the physician's advice. It should not be used during breast feeding.