Aconitine

Name: Aconitine
SKU: 1762987640-2852
Availability: InStock

in Analytical

Sku: 1762987640-2852

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Features

Product Info Cas No. 302-27-2 Purity ?95% Formula C34H47NO11 Formula Wt. 645.74 Chemical Name (1?,3?,6?,14?,15?,16?)-20-Ethyl-1,6,16-trimethoxy- 4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate IUPAC Name [(1S,2R,3R,4R,5R,6S,7S,8R,9R,13R,14R,16S,17S,18R)-8-acetyloxy-11-ethyl-5,7,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate Synonym 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diyl 8-acetate 14-benzoate: Acetylbenzoylaconine Melting Point 204?C Solubility Soluble in water (0.3 mg/mL) or ethanol (35 mg/mL). Appearance White Crystal

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Description

Description

Aconitine is a toxin found in Aconitum that exhibits antipyretic, antihypertensive, analgesic, and antinociceptive activities. Aconitine binds neurotoxin binding site 2 of Na+ channels, forcing the channel to stay open longer, allowing continual depolarization, Na+ influx, and eventually paralysis. Aconitine acts as a positive inotrope, potentially inducing cardiac arrhythmia.

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