AdipoRon Hydrochloride (water soluble)

in Analytical
Sku: 1762987569-2837
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Product Info Purity ?98% Formula C27H28N2O3?HCl?H2O Formula Wt. 483.01 IUPAC Name 2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;hydrochloride;hydrate Solubility Highly soluble in DMSO. Soluble in 100% ethanol or methanol. Slightly soluble in water (1mg/ml). Appearance White solid
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Description

AdipoRon is an agonist at adiponectin receptors that increases secretion of AMPK and PPAR-?. AdipoRon exhibits anti-diabetic and cardioprotective activities and is in development as a potential treatment for type 2 diabetes mellitus (T2DM). In vivo, AdipoRon decreases insulin resistance and glucose tolerance, ameliorates diabetes, and increases lifespan. In animal models of myocardial ischemia/reperfusion, this compound improves cardiac function, decreases oxidative stress, and inhibits post-ischemic cardiomyocyte apoptosis.

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