AHU-377 Tris Salt

in Analytical
Sku: 1762987463-2799
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Product Info Cas No. 149709-62-6 Purity ?99% Formula C24H29NO5 ? C4H11NO3 Formula Wt. 532.63 IUPAC Name 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid Synonym AHU377, Sacubitril Solubility Soluble in DMSO Appearance White to off white powder
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Description

AHU-377 is a prodrug that is metabolized to the active form, LBQ657; this compound inhibits neprilysin, preventing degradation of atrial natriuretic peptide (ANP) and brain-derived natriuretic peptide (BNP). AHU-377 displays vasodilatory and antihypertensive properties. AHU-377 is currently in clinical trials as a potential treatment for several cardiovascular indications such as congestive heart failure (CHF) and hypertension.

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