AK-1 is an inhibitor of sirtuin 2 (SIRT2); sirtuins are considered class III histone deacetylases (HDACs). AK-1 exhibits neuroprotective and anticancer activities. This compound prevents some hippocampal neurodegeneration in animal models of Alzheimer?s disease. AK-1 also induces cell cycle arrest in colon carcinoma cells by downregulating expression of Snail.
Uniformity of Dosage Units
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Uniformity of Dosage Units is a specialised analytical laboratory service that assesses whether individual dosage units contain sufficiently consis...



































