Alfuzosin Hydrochloride

in Analytical
Sku: 1762987436-2790
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Product Info Cas No. 81403-68-1 Purity ?97% Formula C19H27N5O4 ? HCl Formula Wt. 425.91 Chemical Name (2RS)-N-[3-[(4-Amino-6, 7-dimethoxyquinazolin-2-yl)methylamino]propyl]tetrahydrofuran-2-carboxamide hydrochloride IUPAC Name N-[3-[(4-amino-6, 7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide; hydrochloride Melting Point 229-231C Appearance White to off white powder Crystalline
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Description

Alfuzosin is an ?1-adrenergic receptor antagonist that is used clinically to treat benign prostatic hyperplasia (BPH); it relaxes prostatic smooth muscle and increases the urinary flow rate. Alfuzosin also delays cardiac repolarization by increasing the Na+ current. This compound prolongs action potential duration and the QT interval in vivo by increasing the probability of hNa(v)1.5 channel openings and burst duration.

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