ALLN

in Analytical
Sku: 1762987403-2784
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Product Info Cas No. 110044-82-1 Purity ?98% Formula C20H37N3O4 Formula Wt. 383.53 IUPAC Name 2-acetamido-4-methyl-N-[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]pentanamide Synonym Calpain inhibitor 1, Ac-LLnL-CHO, MG-101, N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal Melting Point 267.52?C (Predicted) Solubility Soluble in DMSO (10 mg/ml), ethanol (5 mg/ml), methanol, and DMSO. Insoluble in water, and aqueous buffers. Appearance White Powder
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Description

ALLN is a tetrapeptide that inhibits proteases such as calpain I and II. ALLN also stimulates autophagy in vitro and suppresses I?B proteolysis. ALLN exhibits anticancer chemotherapeutic and chemopreventive potential, inducing apoptosis in colon cancer cells and inhibiting tumor formation in vivo.

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