Ambalta Capsules SpecificationRequires Prescription (YES/NO)YesGenericsDuloxetine hydrochlorideUsed ForDepressionHow it worksAlthough the exact mechanisms of the antidepressant, central pain inhibitory and anxiolytic actions of duloxetine in humans are unknown, these actions are believed to be related to its potentiation of serotonergic and noradrenergic activity in the CNS.Ambalta Capsules Usage And SafetyDosageDuloxetine hydrochlorideSide EffectsGI disorders , excessive sweating CNS disorders e.g. dizziness , fatigue , insomnia , somnolence , blurred vision , dysuria , headache , dry mouth , wt loss , palpitation , tremor , tinnitus , muscle spasms , anorexia, increased libido , anxiety , abnormal dreams.Drug InteractionsCYP1A2 Inhibitors , CYP2D6 Inhibitors , tricyclic antidepressants [TCAs], such as nortriptyline, amitriptyline, and imipramine), phenothiazine and Type 1C anti-arrhythmic (e.g., propafenone, flecainide), Alcohol.IndicationIt is used in depression, anxiety, neuropathic and muscular pain.When not to UseThe use of MAOIs intended to treat psychiatric disorders with duloxetine or within 5 days of stopping treatment with duloxetine is contraindicated because of an increased risk of serotonin syndrome.Ambalta Capsules PrecautionsPrecautionPatients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.Ambalta Capsules WarningsWarning 1It should be discontinued in patients who develop jaundice or other evidence of clinically significant liver dysfunction and should not be resumed unless another cause can be established.Warning 2Orthostatic hypotension and syncope have been reported with therapeutic doses of duloxetine. Syncope and orthostatic hypotension tend to occur within the first week of therapy but can occur at any time during duloxetine treatment, particularly after dose increases.Warning 3Severe skin reactions, including erythema multiforme and Stevens-Johnson Syndrome (SJS), can occur with Duloxetine.Ambalta Capsules Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.