Amorolfine Hydrochloride

in Analytical
Sku: 1762987287-2742
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Product Info Cas No. 78613-38-4 Purity ?98.5% Formula C21H35NO ? HCl Formula Wt. 353.97 Chemical Name (2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride IUPAC Name (2R,6S)-2, 6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl] morpholine;hydrochloride Melting Point 204-206?C Solubility Slightly soluble in water, less soluble in HCl solution Appearance White Crystal Powder
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Description

Amorolfine is an antifungal compound that prevents ergosterol synthesis through the inhibition of sterol 14?-demethylase. Amorolfine increases release of prostaglandin D2 metabolites, inhibiting release of thromboxane B2 (TxB2), activation of NF-?B, and production of thymic stromal lymphopoietin; as a result, inflammation in atopic dermatitis models is decreased.

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