Amosar Forte 100 / 25?mg ( Hydrochlorothiazide + Losartan?) 30 film-coated?tablets
Why it’s used
Amosar Forte Tablet?is used to treat an essential high blood pressure condition in patients who are suffering from the state of uncontrolled blood pressure on losartan or hydrochlorothiazide alone. It is a prescription medicine. Hydrochlorothiazide works by eliminating the excess of water,?sodium?and?potassium?salts?from the kidney and losartan works by?preventing?the activity of certain natural substances that tighten the blood vessels which results in decreased blood pressure. Amosar Forte is also used to reduce the risk of?stroke?and high blood pressure conditions in patients with enlarged heart (left ventricular hypertrophy).
Angiotensin 2 Receptor Blocker
Amosar Forte?belongs to a class of medicines called?Angiotensin 2 Receptor Blocker. Angiotensin II receptor blockers are used for the treatment of high blood pressure and heart failure. These medicines act by relaxing the blood vessels and makes it easier for your heart to pump blood.
How to use
Follow directions on the product label, information guide, and provided by your doctor before using?Amosar Forte. Eat this?medicine?as per your doctor’s instructions.
Amosar Forte?is eaten with or without food.
The typical adult dose of Amosar Forte is 50 mg/12.5 mg once daily (not more than 100 mg/25 mg once daily). The maximum dose for adults of?Amosar Forte?is 100/25 mg once daily per day.
Amosar Forte is to be used for longer periods of time. Use of Amosar Forte may be prescribed for the long-term to control the high blood pressure conditions in patients with?creatinine?clearance less than 30 ml/min.
Tell your doctor if you develop new or worsening symptoms. Talk to your doctor if?nausea,?pain?in the right upper stomach area, yellow eyes or skin, swelling in the feet, ankles, or hands, unexplained weight gain, and inflammation of the connective tissues (systemic?lupus?erythematosus). Consult with your doctor before stopping the use of Amosar Forte Tablet.
Avoid?drinking?alcohol?with Amosar Forte.
Medicines may be given for uses other than those listed in the medicine guide. Do not use?Amosar Forte Tablet?for symptoms for which it was not prescribed. Do not give Amosar Forte Tablet to others who may have similar symptoms as you. Self-medication can cause harm.
Store?Amosar Forte Tablet?at 25?C (77?F), away from moisture, and away from light. Keep this?medicine?away from children and?pets.
Read more:?What are the uses of Amosar Forte?
How to take Amosar Forte
Your dose and how often you take?Amosar Forte?will depend on the following factors:
age
patient’s health
response to the?medicine
Amosar Forte?Dosage
Dosage for?severe conditions of high blood pressure
Adult
Recommended: 50/12.5 mg once daily
Maximum: 100/25 mg once daily after 2 to 4 weeks of therapy
Dosage for?patients who are suffering from the state of uncontrolled blood pressure on losartan or hydrochlorothiazide alone
Adult
Initial: 50/12.5 mg once daily and patients who do not respond to 50/12.5 mg after 2 to 4 weeks of therapy, the dosage should be increased up to 100/25 mg/day
Maximum: 100/25 mg once daily
Dosage for?high blood pressure conditions in patients with enlarged heart
Adult
Initial: 50/12.5 mg/day (for inadequate blood pressure reduction) and 100/12.5- 100/25 mg/day (for additional blood pressure reduction)
Forms
Tablet
Strength:?50/12.5 mg, 100/12.5 mg, 100/25 mg
Missed Dose
Take the missed dose as soon as you remember. Do not take a second dose to make up for the dose that you may have missed. Just continue with the next dose.
Overdose
What to do if you overdose on Amosar Forte?
In case of overdosage, symptomatic (treatment according to the symptoms) and supportive therapy should be given. If ingestion is recent, the harmful effect can be reduced by inducing?emesis?and by correction of?dehydration. The patient should be observed for?electrolyte?imbalance,?liver?coma, and low blood pressure. Overdose effect of?losartan?can be removed from the blood by artificial blood purifying technique (hemodialysis).
Symptoms of an overdose of Amosar Forte
If you use too much of this medicine, it could lead to dangerous levels of the medicine in your body. In such cases, symptoms of an overdose may include:
dehydration
electrolyte depletion including low levels of?potassium, chloride and?sodium?ions in the blood
low blood pressure
rapid heart rate
slow heart rate
If you think you have overdosed on Amosar Forte Tablet, call a poison control center immediately. You can look up the poison control center information from the?Poison Center Finder?at TabletWise.com.
Precautions while using Amosar Forte
Before you use?Amosar Forte, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Discuss with your doctor if you are allergic to sulfonamide-derived drugs.
Before you use?Amosar Forte Tablet, tell your doctor of your medical history including swelling of the face, lips, throat, or tongue, mild to moderate?liver?problems, bronchial?asthma, blood vessel related heart and?brain?diseases, sulfonamide,?aspirin?or?penicillin?allergy, kidney problems, heart attack, enlargement of the heart muscle tissue (left ventricular hypertrophy), difficulty in passing urine (anuria),?diabetes, essential high blood pressure, reduce fluid volume in the body (intravascular volume depletion), heart failure, narrowing of the arteries of the kidney (bilateral kidney artery?stenosis?or stenosis of the artery to a solitary kidney), excessive?secretion?of aldosterone (primary aldosteronism), absence of?lactase?(galactose?intolerance, the Lapp?lactase?deficiency), abnormal absorption of?glucose?and galactose, abnormal quantities of?protein?in the urine,?alcoholic?cirrhosis?of the liver,?stroke,?aliskiren,?potassium?supplements,?salt?substitutes containing?potassium, use of?water?pills?(diuretics),?lithium?and non-steroidal anti-inflammatory drugs (NSAIDs), low?potassium, low?sodium?or high?calcium?levels, salt-restricted?diet, severe vomiting and/or?diarrhea, kidney transplantation, narrowing of the arteries (atherosclerosis), chest?pain?(angina?pectoris), narrowing of the valves of the heart (aortic or mitral valve stenosis), or progressive liver disease. When?losartan?is used in a patient with?alcoholic?cirrhosis of the liver, the level of losartan may increase. In patients with liver disease, minor changes of fluid and?electrolyte?balance?may cause liver?coma. In patients with asthma or with a history of allergy, allergic reactions may occur. Use of Amosar Forte in patients with diabetes, may cause?electrolyte?imbalances. Use of losartan in patients with aspirin or?penicillin?allergy may cause swelling of the lips and eyelids and facial rash. In patients with essential high blood pressure and narrowing of the kidney arteries, this medicine may increase the level of?creatinine?and?urea?nitrogen?in the blood. Use of Amosar Forte in patients with heart failure and reduced fluid volume in the body (intravascular volume depletion) may cause low blood pressure. Use of Amosar Forte in patients with blood vessel-related heart and brain disease may decrease blood pressure which may result in heart attack or stroke. Use of Amosar Forte in patients with kidney problem may increase the risk of progressive azotemia (abnormally high levels of the nitrogen-containing compound) with kidney failure,?electrolyte?balance, decreased the production of urine, and possibly fatal. The patients with a history of sulfonamide or?penicillin?allergy have a risk of developing an eye disease that can cause blindness.
The use of Amosar Forte Tablet may change hemoglobin and hematocrit value. A small decrease in hemoglobin and hematocrit value has been reported in patients while using this medicine.
The use of this medicine may change blood?creatinine?levels. A minor increase in blood creatinine level has been reported in patients while using this medicine.
The use of Amosar Forte Tablet may change blood urea nitrogen. A minor increase in blood urea nitrogen level has been seen in patients while using this medicine.
The use of this medicine may change bilirubin levels in the blood. Increased levels of bilirubin have been seen in patients while using this medicine.
The use of this medicine may change liver enzymes level. The increase in the level of liver enzymes have been seen in patients while using this medicine.
Amosar Forte Tablet is not safe for use in women who are?pregnant. If you are pregnant or planning to become pregnant, you should discuss the impact on the fetus with your doctor before you start using this medicine. Amosar Forte may act directly on the renin-angiotensin system when used during the second and third trimesters of?pregnancy. This may cause injury to the developing fetus such as low blood pressure, abnormal brain growth (neonatal skull hypoplasia), nonpassage of urine (anuria), kidney failure, decreased functioning of the kidney, high?potassium?levels, prematurity, fetal growth restriction (intrauterine growth retardation), heart problem (patent ductus arteriosus), deficiency of amniotic fluid (oligohydramnios) and is possibly fatal to the unborn baby. Thiazides may cross the placenta and this may cause birth defects such as low levels of thrombocytes,?jaundice?(icterus), electrolyte disturbances and other side effects that occurred in adults. Consult with your doctor on the use of Amosar Forte Tablet during?breastfeeding. This medicine is excreted in breast milk and may cause serious side effects in infants. This medicine should not be used during?breastfeeding?and if the use of Amosar Forte is necessary, the lowest doses should be considered. Consult with your doctor on the use of Amosar Forte Tablet, if you are trying to conceive.
Avoid?drinking?alcohol?with?Amosar Forte. Consumption of alcohol may cause low blood pressure while standing up from sitting or lying down.
Amosar Forte can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of?alcohol?with Amosar Forte can worsen the sleepiness. Amosar Forte may cause?seizures?in some people. Hence, you should discuss with your doctor before performing any activities where a loss of consciousness may cause harm to you or others.
This medicine may increase your sensitivity to sunlight and make you prone to?sunburn. If this happens, limit your time outdoors to prevent sunburn. Use a sunscreen and cover your skin when you are outdoors. If you get sunburns on your body, consult with your doctor.
Read more:?What precautions should be taken during Pregnancy and Nursing, and administering Amosar Forte to Children or the Older Adults?
Amosar Forte Side-effects
The following side-effects may commonly occur when using?Amosar Forte Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
back pain
chest pain
cough
decrease in the level of hematocrit and haemoglobin
diarrhea
dizziness
fast or irregular heartbeat
fatigue
headache
high blood?potassium?levels
indigestion
inflammation of the pharynx
inflammation or swelling of the sinuses
insomnia
irritation and inflammation of the airways
kidney failure
kidney problem
lack of energy
leg?pain
low blood sugar
low blood sugar levels
mild reduction of haematocrit and haemoglobin
muscle cramp
muscle?pain
nausea
rash
sinus disorder
stomach?pain
stuffy nose (nasal congestion)
upper respiratory infection
Rarely, the use of Amosar Forte Tablet may cause the following side-effects:
abnormal dreams
arm?
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