Anastrozole

in Analytical
Sku: 1762987181-2722
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₦1,820,190.00

Product Info Cas No. 120511-73-1 Purity ?99% Formula C17H19N5 Formula Wt. 293.37 Chemical Name 2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile) IUPAC Name 2-[3-(2-cyanopropan-2-yl)-5-(1,2, 4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile Synonym ZD1033 Pure, Zeneca ZD1033 Melting Point 81-84?C Solubility soluble in methanol, acetone, ethanol (59 mg/mL), THF, ethyl acetate, chloroform, DMSO (40 mg/mL). Slightly soluble in water. Appearance White Crystal Powder
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Description

Anastrozole is a third generation aromatase inhibitor that suppresses synthesis of estrogen. Anastrozole exhibits anticancer chemotherapeutic activity and is clinically used to treat ER-positive breast cancer. In vitro, anastrozole inhibits proliferation of cancer cells by disrupting the mitochondrial membrane potential and inducing apoptosis. Because of its anti-estrogen properties, anastrozole may decrease bone mineral density and increase fracture risk.

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