AP-26113

in Analytical
Sku: 1762987030-2696
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Product Info Cas No. 1197958-12-5 Purity ?98% Formula C26H34ClN6O2P Formula Wt. 529.02 IUPAC Name 5-Chloro-N2-{4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl}-N4-[2-(dimethylphosphoryl)phenyl]-2,4-pyrimidinediamine Synonym Brigatinib Analog, AP26113
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Description

AP-26113 (brigatinib) is a pan inhibitor of ALK. It is a leading candidate for the treatment of ALK+ non-small-cell lung cancer, especially those with major resistance mechanisms. AP-26113 exhibits efficacy against models of ALK+ anaplastic large cell lymphoma in cases where crizotinib, an approved drug for late-stage and metastatic lung cancers, fails due to developed drug resistance.

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