AZD-4547

in Analytical
Sku: 1762986576-2613
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Product Info Cas No. 1035270-39-3 Purity ?98% Formula C26H33N5O3 Formula Wt. 463.57 IUPAC Name N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]benzamide Synonym AZD-4547 Solubility DMSO 92 mg/mL (198.45 mM) Water Insoluble Ethanol Insoluble Appearance White to off white powder
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Description

AZD-4547 is an inhibitor of FGFR that is somewhat selective for FGFR2 over FGFR1 and FGFR3; it exhibits anticancer chemotherapeutic activities. This compound is currently in clinical trials as a potential treatment for breast cancer. In breast cancer cells, AZD-4547 induces apoptosis and inhibits cellular proliferation, invasion and migration. In vivo, this compound inhibits tumor growth and metastasis.

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