Bafilomycin A1

in Analytical
Sku: 1762986447-2585
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₦2,281,910.00

Product Info Cas No. 88899-55-2 Purity ?90% Formula C35H58O9 Formula Wt. 622.83 IUPAC Name (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2, 4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8- hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11, 13-tetraen-2-one Solubility Soluble in DMSO, ethanol and methanol. Appearance White to off white powder
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Description

Bafilomycin A1 is a macrolide antibiotic initially produced by Streptomyces that exhibits anti-parasitic, antimalarial, and anticancer chemotherapeutic activities. Bafilomycin A1 inhibits the vacuolar H+ ATPase and suppresses autophagy. Bafilomycin kills Plasmodium parasites in cellular models, and separately, induces cell death and suppresses tumor growth in animal models of breast cancer.

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