Bafilomycin B1

Name: Bafilomycin B1
SKU: 1762986443-2584
Availability: InStock

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Sku: 1762986443-2584

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Features

Product Info Cas No. 88899-56-3 Purity ?97% Formula C44H65NO13 Formula Wt. 815.99 Chemical Name Hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)carbonyl)-2-methoxy-24-methyl- IUPAC Name [(2R,4R,5S,6R)-2-hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(3S,4Z,6Z,9S,10S, 11R,12Z,14E)-10-hydroxy-3,15-dimethoxy-7,9,11, 13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12, 14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl] (E)-4-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-4-oxobut-2-enoate Synonym Setamycin Melting Point 89-96?C (dec) Solubility Soluble in methanol. Appearance Yellow Powder

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Description

Description

Bafilomycin B1 is a macrolide antibiotic that also exhibits antifungal activity. Bafilomycin B1 inhibits the vacuolar H+ ATPase. Additionally, bafilomycin B1 inhibits Foxo1 and increases ? cell apoptosis, accelerating the onset of diabetes.

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