Berberine (chloride) 1 G

Product Overview?Berberine is an isoquinoline alkaloid that has been found in?C. fenestratum?and has diverse biological activities.It induces frameshift mutations and gene crossovers in haploid and diploid strains of?S. cerevisiae?in the exponential growth phase, respectively, when used at a concentration of 50 ?g/ml.?Berberine is active against the?S. aureus?strains ATCC 25922 and NCTC 8530 (MIC = 250 ?g/ml for both)?It decreases contusion volume, ventricle enlargement, and neurological deficits in a mouse model of controlled cortical impact-induced traumatic brain injury (TBI) when administered at a dose of 10 mg/kg.Berberine (50 mg/kg) reduces serum LDL cholesterol levels in hamsters fed a high-fat high-cholesterol diet.5WARNING?This product is?not?for human or veterinary use.Formal Name5,6-dihydro-9,10-dimethoxy-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, monochlorideCAS Number633-65-8SynonymsBBRUmbellatineNSC 163088NSC 646666Molecular FormulaC20H18ClNO4Formula Weight371.8FormulationA crystalline solidSolubilityDMF: 500?g/mlDMSO: 25 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.2 mg/mlEthanol: 500?g/ml?max230, 266, 348, 431 nmSMILESCOC1=C2C(C=C3[N+](CCC4=C3C=C5C(OCO5)=C4)=C2)=CC=C1OC.[Cl-]InChi CodeInChI=1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1InChi KeyVKJGBAJNNALVAV-UHFFFAOYSA-MOriginSynthetic??Write a review Your Name Your ReviewNote: HTML is not translated! Rating Bad Good Captcha Please complete the captcha validation below Continue