Chidamide impurity – 98%, high purity , CAS No.743420-02-2, Inhibitor of histone deacetylase 1

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Sku: 1759801454-3143
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Canonical SmilesC1=CC(=CN=C1)C=CC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=CC(=C3)F)N IUPAC NameN-(2-amino-5-fluorophenyl)-4-[[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide InChIKeyWXHHICFWKXDFOW-BJMVGYQFSA-N INCHI1S/C22H19FN4O2/c23-18-8-9-19(24)20(12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H,14,24H2,(H,26,28)(H,27,29)/b10-5+ Isomeric SMILES C1=CC(=CN=C1)/C=C/C(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=CC(=C3)F)N Alternate CAS 1883690-47-8 Molecular Weight 390.41 Reaxy-Rn 20992484 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20992484&ln=
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Description

Chidamide is an HDAC (histone deacetylase) inhibitor that increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 ?M.

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