Tegral tablets 200 mg 5_10?s

Tegral tablets 200 mg 5_10?s is a sodium channel blocker.[34] It binds preferentially to voltage-gated sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential. This drug has effects on serotonin systems but the relevance to its antiseizure effects is uncertain. There is evidence that it is a serotonin releasing agent and possibly even a serotonin reuptake inhibitor.
Side effects
Major & minor side effects for Tegral tablets 200 mg 5_10?s

Blurred vision severe

Diarrhea severe

Nausea or Vomiting severe

stiffness of limbs severe

Headache severe

Drowsiness severe

Frequent urination severe

Weight gain severe

Yellow colored eyes or skin severe

Dry mouth

Increased sweating

Skin Rash

Uses of Tegral tablets 200 mg 5_10?s
What is it prescribed for?

Epilepsy
Tegral tablets 200 mg 5_10?s is used in the treatment of Epilepsy which is a brain disorder that causes repeated seizures. Uncontrolled jerking movements and loss of consciousness are some of the symptoms of Epilepsy.

Trigeminal Neuralgia
Tegral tablets 200 mg 5_10?s is used in the treatment of trigeminal neuralgia which is a condition that affects the nerve that carries sensations from face to the brain characterized by chronic pain

Concerns

Frequently asked questions

Onset of action
The peak effect of this medicine can be observed in 4.5 hours for immediate-release tablets, 3 to 12 hours for extended-release tablets and 1.5 hours for oral suspension.

Duration of Effect
The effect of this medicine lasts for an average duration of 2 to 3 days

Safe with Alchohol?
Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.

Is it habit forming?
No habit forming tendency has been reported.

Usage in pregnancy?
This medicine is not recommended for pregnant women.

Usage while breast-feeding?
This medicine is recommended only if clearly needed when no safer alternative is available. Monitoring of undesired effects like discoloration of eyes and skin is necessary, drowsiness, and weight gain is necessary.

When not to use?

Allergy
Avoid if you have a known history of allergy to Tegral tablets 200 mg 5_10?s .

Bone marrow suppression
Do not use this medicine if you have a history of bone marrow suppression or any blood disorder.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for pregnant women.

Pregnancy
This medicine is recommended only if clearly needed when no safer alternative is available. Monitoring of undesired effects like discoloration of eyes and skin is necessary, drowsiness, and weight gain is necessary.

General Warnings

Suicidal thoughts
Use of Tegral tablets 200 mg 5_10?s may increase the risk of suicidal thoughts or depression. Therefore this medicine should be used with caution and prescription size should be limited in patients with depression or suicidal tendencies.

Skin reactions
Tegral tablets 200 mg 5_10?s may cause severe skin reactions like stevens-johnson syndrome and toxic epidermal necrolysis. Inform the doctor if any symptoms appear and discontinue the treatment as early as possible.

Blood cell count
Tegral tablets 200 mg 5_10?s may cause agranulocytosis and aplastic anemia. Frequent monitoring of blood cell count is necessary.

Withdrawal symptoms
Tegral tablets 200 mg 5_10?s should not be stopped immediately without informing the doctor due to the risk of withdrawal symptoms like convulsions, behavioral disorder, tremor, and anxiety. Gradual dose reduction should be made based on the outcomes in the patient.

Impaired liver function
Tegral tablets 200 mg 5_10?s should be used with caution in the patients with mild to moderate liver injury. Lowest possible doses should be initiated and increase the dose based on the patient’s response. This medicine is not recommended in the patients with severe liver injury.

Impaired kidney function
Use with caution in the patients with the kidney injury. Half of the usual starting dose should be administered if CrCl is less than 50 ml/min.

Dosage

Missed Dose
If you miss a dose of Tegral tablets 200 mg 5_10?s , take the missed dose as soon as you remember. If it?s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Diltiazem severe

Ethinyl Estradiol moderate

Azole antifungal agents severe

Disease interactions

severe
Tegral tablets 200 mg 5_10?s should be given with caution in the patients with depression and suicidal thoughts. Frequent monitoring of depression symptoms is necessary. Dose adjustments are to be made based on the outcomes in the patient.

severe
Tegral tablets 200 mg 5_10?s should be used with caution in the patients with the mild to moderate liver disease. Frequent monitoring of liver function tests is necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

General Instructions

Take Tegral tablets 200 mg 5_10?s with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause seizures.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

References

wikipedia –
Carbamazepine [Internet].
Available from: https://en.wikipedia.org/wiki/Carbamazepine#:~:text=is%20given%20repeatedly.-,Mechanism%20of%20action,firing%20of%20an%20action%20potential.
[cited 30/6/2020].
22/6/2020

webmd.com –
Carbamazepine [Internet].
Available from: https://www.webmd.com/drugs/2/drug-1493-5/carbamazepine-oral/carbamazepine-oral/details
[cited 30/6/2020].