INTRODUCTION
CRAVIHENZ 40 TABLET contains Megestrol which belongs to the group of medicines called Progestogens. CRAVIHENZ 40 TABLET is used to treat hormone dependent cancer which includes breast and endometrial cancer in affected individuals.
CRAVIHENZ 40 TABLET is also used to treat reduced appetite & weight-loss in patients passing through an advanced stage of cancer/HIV.
CRAVIHENZ 40 TABLET is not recommended for use in patients allergic to Megestrol.
Before taking CRAVIHENZ 40 TABLET, inform your doctor if you have diabetes, thrombophlebitis (blood clot due to inflammatory process), intolerance to certain sugars (such as lactose), kidney problems (such as chronic kidney disease), and/or severe liver problems.
CRAVIHENZ 40 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women.
CRAVIHENZ 40 TABLET is not generally recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.
The most common side effects of taking CRAVIHENZ 40 TABLET are increase in appetite, shortness of breath, high blood pressure, hot flushes, nausea, vomiting, passing wind, and/or constipation. Consult your doctor if any of these side effects worsens.?
USES OF CRAVIHENZ 40 TABLET

Treats hormone dependent cancer which includes breast and endometrial cancer.

Treats reduced appetite & weight-loss in patients passing through an advanced stage of cancer/HIV

HOW CRAVIHENZ 40 TABLET WORKS
CRAVIHENZ 40 TABLET works by changing the hormone balance in the body which results in interference of growth in hormone dependent cancer cells which leads to inhibition of growth and spread of cancer cells thus treating hormone dependent cancer (including breast and endometrial cancer) in affected individuals.
DIRECTIONS FOR USE
Take CRAVIHENZ 40 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF CRAVIHENZ 40 TABLET

COMMON

Increase in appetite, weight gain

Shortness of breath, high blood pressure

Hot flushes, reddening of the face/neck, round face (moon face)

Increased blood sugar

Tiredness, feeling weak, nausea, vomiting, passing wind, constipation, diarrhea

Swelling of a vein (due to blood clot)

Changes in mood, numbness, pain, and/or tingling sensation in fingers/thumb

Hair loss

Impotence

Needing to urinate often

Changes in vaginal bleeding (breakthrough bleeding/spotting)

Buildup of fluid which causes swelling (especially in ankles)

Pain, rash, red itchy welts

RARE
Stop taking CRAVIHENZ 40 TABLET and contact your doctor immediately if you experience any of the following side effects:
Signs of blood clot such as loss of coordination, slurred speech, pain in groin, pain/ numbness in arm/leg, shortness of breath, weakness, headache, and/or fainting.

Signs of allergic reaction such as swelling of face/lips/tongue, skin rash, and/or difficulty in breathing

HOW TO MANAGE SIDE EFFECTS
Diarrhea:
Drink lot of fluids such as water/fruit juice to keep yourself hydrated. Do not take any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.
Constipation:
Eat fiber rich foods such as fresh fruits, vegetables, cereals and drink enough water. Exercise more regularly. Consult your doctor if the symptom does not improve.
Nausea/Vomiting:
Stick to simple meals and avoid eating oily or spicy food. Do not perform any strenuous activity immediately after eating. If the symptom does not improve, contact your doctor.
Tiredness:
Drink plenty of fluids and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS

PREGNANCY
CRAVIHENZ 40 TABLET is generally not recommended for use during pregnancy and in women planning for pregnancy. Consult your doctor before taking the medicine.
BREASTFEEDING
CRAVIHENZ 40 TABLET is not generally recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
DRIVING AND USING MACHINES
CRAVIHENZ 40 TABLET is unlikely to affect your ability to drive/operate machines. Consult your doctor before taking CRAVIHENZ 40 TABLET.
KIDNEY
CRAVIHENZ 40 TABLET should be used with caution in patients with kidney problems such as chronic kidney disease. Consult your doctor before taking CRAVIHENZ 40 TABLET.
LIVER
CRAVIHENZ 40 TABLET should be used with caution in patients with severe liver problems. Consult your doctor before taking CRAVIHENZ 40 TABLET.
ALLERGY
Do not take CRAVIHENZ 40 TABLET if you are allergic to Megestrol, and/or any other ingredients of this medicine.
OTHERS
Before taking CRAVIHENZ 40 TABLET, inform your doctor if you:
Have diabetes

Currently suffer/have a history of thrombophlebitis (blood clot due to inflammatory process)

Intolerance to certain sugars such as lactose.
Use in Pediatrics:
CRAVIHENZ 40 TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before administering the medicine to the child.
Use in Geriatrics:
CRAVIHENZ 40 TABLET should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking CRAVIHENZ 40 TABLET.
INTERACTIONS
A. Drug ? Drug interactions:
Inform your doctor if you are taking any medicines including prescription, non-prescription, over the counter medicines, vitamins, and/or herbal supplements before taking this medicine.
Overdosage:
If you or anyone else accidentally take too much of CRAVIHENZ 40 TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
SYNOPSIS

Drug :?? Megestrol

Pharmacological Category :?? Progestins

Therapeutic Indication :?? Hormone-dependent cancers (Breast cancer, Endometrial Cancer), Reduces appetite & weight-loss in patients (in advanced stage of cancer/HIV)

Dosage Forms :?? Tablet

MORE INFORMATION

Keep CRAVIHENZ 40 TABLET out of reach of children

?Do not store CRAVIHENZ 40 TABLET above 25?C

FAQs ABOUT CRAVIHENZ 40 TABLET
What is CRAVIHENZ 40 TABLET used for?
CRAVIHENZ 40 TABLET is used to treat hormone dependent cancer which includes breast and endometrial cancer in affected individuals. It is also used to treat reduced appetite & weight-loss in patients passing through an advanced stage of cancer/HIV.
What are the side effects of CRAVIHENZ 40 TABLET?
The most common side effects of taking CRAVIHENZ 40 TABLET are increase in appetite, shortness of breath, high blood pressure, hot flushes, nausea, vomiting, passing wind, and/or constipation. Consult your doctor if any of these side effects worsens.?
Can CRAVIHENZ 40 TABLET be used in pregnant and breastfeeding women?
No, CRAVIHENZ 40 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
How CRAVIHENZ 40 TABLET works?
CRAVIHENZ 40 TABLET works by changing the hormone balance in the body which results in interference of growth in hormone dependent cancer cells which leads to inhibition of growth and spread of cancer cells thus treating hormone dependent cancer (including breast and endometrial cancer) in affected individuals.
What happens if CRAVIHENZ 40 TABLET is taken more than its required dosage?
If you or anyone else accidentally take too much of CRAVIHENZ 40 TABLET, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.
REFERENCES
1. KD Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology.? Seventh Edition. 2013. Page ? 316.
2. Lori D Wazny, Stewart Nadurak, Cali Orsulak, Lori Giles-Smith, Navdeep Tangri. The Efficacy and Safety of Megestrol Acetate in Protein-Energy Wasting due to chronic kidney disease: A Systematic Review. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. May 2016. [Accessed on 3rd December 2022] https://pubmed.ncbi.nlm.nih.gov/26776251/
3. Haupt Pharma Amareg GmbH. Electronic Medicines Compendium (EMC). [Revised in September 2022] [Accessed on 3rd December 2022] https://www.medicines.org.uk/emc/files/pil.11135.pdf
4. MediArt Life Sciences Pvt. Megacet-40. [Accessed on 3rd December 2022] https://www.mediartlifesciences.com/megacet-40/
USEFUL DIAGNOSTIC TESTS

Blood tests

Computerized tomography (CT) scan

Positron emission tomography (PET) scan

PRODUCT DETAILS

Country Of Origin

India

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