EXODEP 75 Tablet 10?s Allschoolabs -

Description

INTRODUCTION
EXODEP 75 contains Dosulepin which belongs to the group of medicines called Antidepressants. It is used in the treatment of depression (mood disorder causing persistent feeling of sadness and loss of interest) and also helps to reduce the feelings of anxiety (intense, excessive, persistent worry and fear about everyday situations), this medicine is used only when other medicines are not suitable. ?
EXODEP 75 is not recommended for use in patients with liver problems, irregular heartbeat or any other heart problems, mania (feeling over excited with unusual behaviour), glaucoma (increased pressure in eye), prostate problems and fits.
Before taking EXODEP 75 inform your doctor if you have any planned surgeries (such as dental or general surgery), intolerance to certain sugars and thyroid problems. Avoid consumption of alcohol during treatment with EXODEP 75 as it can make the drowsiness worse. ???
EXODEP 75 should be used in pregnant and breast-feeding women only if clearly advised by the doctor. It is not recommended for use in children and adolescents (below the age of 18 years) and it should be used with caution in elderly patients due to increased risk of certain side effects. ?
The most common side effects of taking EXODEP 75 are dry mouth, blurred vision, dizziness, constipation, sedation and difficulty in passing urine. Consult with your doctor if any of the side effect worsens.
USES OF EXODEP 75

Treats depression

Reduce the feelings of anxiety

HOW EXODEP 75 WORKS
EXODEP 75 acts on central nervous system (CNS) which works by enhancing the activity of certain neurotransmitters (such as serotonin and noradrenaline) in the brain. It also works by stopping the reabsorption of neurotransmitters into the nerve cells in the brain. Thus, results in prolonging their effects and helps to relieve depression and lighten the mood.
DIRECTIONS FOR USE
Take EXODEP 75 as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF EXODEP 75

COMMON

Dry mouth

Blurred vision

Heartbeat changes

Dizziness

Constipation

Sedation

Difficulty in passing urine

UNCOMMON

Severe allergic reaction (skin rash, itching, swollen face or tongue, collapse, shortness of breath, collapse)

Severe low blood pressure

Increased sweating

Tiredness or sleepiness

Confusion and hallucination (strange vision or sounds)

Tremors

Changes in libido (sex drive)

RARE

Severe mood changes such as extreme excitability
Stop taking EXODEP 75 and inform your doctor immediately if you experience any of the following side effects:
Skin rash or difficulty in breathing

Thoughts of harming or killing yourself

Bone marrow depression or reduction in some blood cells (signs include unusual bruising, abnormal bleeding, mouth ulcers, sore throat and fever)

Liver problems associated with yellowing of the skin and eyes (jaundice)

Convulsions (fits)

Irregular heartbeat (more common with high dosage)

HOW TO MANAGE SIDE EFFECTS
Constipation:
Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatment for constipation.
Dry mouth:
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Dizziness:
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.
Tiredness:
Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom gets worse.
WARNING & PRECAUTIONS

PREGNANCY
EXODEP 75 should be used in pregnant women only if clearly advised by your doctor. Consult your doctor before taking it.
BREASTFEEDING
EXODEP 75 should be used in breastfeeding women only if clearly advised by your doctor. Consult your doctor before taking it. ?
DRIVING AND USING MACHINES
Do not drive or use machines if you feel drowsy after taking EXODEP 75. Consult your doctor for advice.
ALCOHOL
Avoid consumption of alcohol during treatment with EXODEP 75 as it can make the feeling of drowsiness worse.
LIVER
EXODEP 75 is not recommended for use in patients with liver problems. Consult your doctor before taking EXODEP 75.
ALLERGY
Do not take EXODEP 75 if you are allergic to Dosulepin or any other ingredients of this medicine.
HEART DISEASE
EXODEP 75 is not recommended for use in patients with irregular heartbeat or any other heart problems. Consult your doctor before taking EXODEP 75.
OTHERS
EXODEP 75 is not recommended for use if you:
Have mania (feeling over excited with unusual behaviour)

Have glaucoma (increased pressure in eye)

Have fits (epilepsy)

Have prostate problems (difficulty in passing urine)
Before taking EXODEP 75 inform your doctor if you:
Have any planned surgeries (general or dental surgery)

Have thyroid problems

Are intolerant to certain sugars
Use in paediatrics:
EXODEP 75 is not recommended for use in children and adolescents (under 18 years of age). Consult child?s doctor for advice.
Use in geriatrics:
EXODEP 75 should be used with caution in elderly patients due to increased risk of side effects such as agitation, confusion and light headedness. Consult your doctor before taking EXODEP 75.
INTERACTIONS
A.?Drug?Drug Interactions:
Before taking EXODEP 75 inform your doctor if you are taking any of the following medicines:
Medicines used to treat depression such as selective serotonin reuptake inhibitor (SSRIs) (Ex. citalopram, fluoxetine) and mono-amine oxidase inhibitor (MAOI) (Ex. isocarboxazid, phenelzine) ??

Medicines used to treat underactive thyroid (Ex. Levothyroxine)

Medicines used to treat epilepsy (Ex. phenobarbitone), insomnia (Ex. amylobarbitone) and behavioural problems (Ex. methylphenidate)

Medicine containing an opioid (Ex. codeine, morphine, dihydrocodeine, co-proxamol and co-dydramol) (used to treat pain)

Medicines used to treat heart problems and asthma (also as cough and cold remedies), sympathomimetic agents (Ex. ephedrine, pseudoephedrine, adrenaline and noradrenaline)

Medicines used to treat high blood pressure (Ex. guanethidine) and regulate heartbeat (Ex. sotalol)

Terfenadine, astemizole (used to treat hay fever or allergy)

Halofantrine (used to treat malaria)
Overdosage:
If you or anyone else accidentally take too much of EXODEP 75, consult your doctor immediately or visit the nearby hospital as it may seriously harm you and cause life-threatening problems.
SYNOPSIS

Drug :??
Dosulepin
Pharmacological Category :??
Tricyclic Antidepressants
Therapeutic Indication :?? Depression, Anxiety

Dosage Forms :??
Tablet
MORE INFORMATION

Keep EXODEP 75 out of reach of children

Store at room temperature

FAQs ABOUT EXODEP 75
What is EXODEP 75 and why is it given?
EXODEP 75 contains Dosulepin which belongs to the group of medicines called Antidepressants. It is used in the treatment of depression and also helps to reduce the feelings of anxiety, this medicine is used only when other medicines are not suitable.??
Can I stop taking EXODEP 75 on my own?
You should not stop taking EXODEP 75 suddenly on your own without the advice of your doctor. Your doctor may gradually withdraw the dose in case of stopping the medicine. If you stop taking EXODEP 75 suddenly you may experience some withdrawal symptoms like irritability, insomnia and excessive perspiration (sweating).
Is EXODEP 75 safe to use in pregnant and breast-feeding women?
EXODEP 75 should be used in pregnant and breast-feeding women only if clearly advised by the doctor. Consult your doctor before taking EXODEP 75 if you are pregnant or planning to get pregnant or breast-feeding your child.
Can I drive or operate heavy machines after taking EXODEP 75?
EXODEP 75 can cause drowsiness. Therefore, it is not advisable to drive or use machineries and tools until you feel normal again. Consult your doctor for advice before taking EXODEP 75.
Can EXODEP 75 be used in elderly patients?
EXODEP 75 should be used with caution in elderly patients due to increased risk of side effects such as agitation, confusion and light headedness. Consult your doctor before taking it.
REFERENCES
1. KD. Tripathi. Antidepressant and Antianxiety Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page ? 459.
2. T Nakagawa, K Ukai, S Kubo. Antidepressive effects of the stereoisomer cis-dosulepin hydrochloride. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 1993 [Accessed on 14th June 2022] https://pubmed.ncbi.nlm.nih.gov/8447840/
3. P Zusky, T C Manschreck, C Blanchard, J Rosenbaum, C Elliot, P Lou. Dothiepin hydrochloride: treatment efficacy and safety. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1986. [Accessed on 14th June 2022]?https://pubmed.ncbi.nlm.nih.gov/3531188/
4.?Dosulepin. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in September 2022] [Accessed on 14th June 2022]?https://pubchem.ncbi.nlm.nih.gov/compound/Dosulepin#section=Mechanism-of-Action
5. Teva Pharmaceuticals Works Pvt Ltd. Dosulepin. [Revised in March 2021]. [Accessed on 14th June 2022]?https://products.tevauk.com/mediafile/id/50662.pdf
6.?Teofarma S.r.l. Health Products Regulatory Authority (HPRA). [Revised in July 2020] [Accessed on 14th June 2022]?https://www.hpra.ie/img/uploaded/swedocuments/0cc11c1c-a57e-470f-a788-57d351b29341.pdf
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