Monzem LC 10/5mg Tablet 10?S Allschoolabs -

Description

INTRODUCTION
MONZEM LC 10/5MG TABLET is a combination of Levocetirizine and Montelukast which belongs to theroup of medicines called H1 receptor antagonists and Leukotriene receptor antagonists respectively. MONZEM LC 10/5MG TABLET is indicated for the treatment and prevention of allergic rhinitis, chronic idiopathic urticaria (allergic skin reaction with red raised itchy bumps on skin) and bronchial asthma in adults and in adolescents (aged 15 years or above).
Allergic rhinitis (also known as hay fever) is a heterogeneous?disorder characterized by inflammation of the inner lining of nose accompanied by?nasal decongestion, repeated sneezing, wheezing, or a red, watery and itchy eyes.
It is usually caused by allergens such as pollens, dusts, mould or flakes of skin from certain animals and can occur seasonally or year-round. Bronchial asthma is a long-term medical condition in which the path of the airways becomes inflamed, narrow and swollen. Symptoms include coughing, wheezing and chest tightness.
MONZEM LC 10/5MG TABLET is contraindicated for use in patients having severe kidney impairment. Consult your doctor before use. Avoid consumption of alcohol while taking MONZEM LC 10/5MG TABLET as it could make you feel drowsier.
MONZEM LC 10/5MG TABLET may cause certain unpleasant neuropsychiatric events (such as anxiety, depression, nightmares, hallucinations or even suicidal thoughts) in some individuals. Contact your doctor immediately if you or anyone else experience such events during treatment with MONZEM LC 10/5MG TABLET.
The most common side effects of taking MONZEM LC 10/5MG TABLET are upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Consult your doctor if any of the side effects worsen.
USES OF MONZEM LC 10/5MG TABLET

Treats and prevents allergic rhinitis, chronic idiopathic urticaria and bronchial asthma in adults and in adolescents (aged 15 years or above)

HOW MONZEM LC 10/5MG TABLET WORKS
MONZEM LC 10/5MG TABLET provides relief from the symptoms of allergic rhinitis, asthma and urticaria where levocetirizine acts by blocking the actions of histamines (a substance that cause allergic reaction), at the H1 receptors present on the surface of cells and montelukast acts by blocking the action of leukotrienes D4 (an inflammatory molecule causing narrowing and swelling of the airways) in the lungs, thus causing relaxation of smooth muscle, reduction in swelling and/or inflammation of the airways and a marked decrease in the onset of allergic reactions.
DIRECTIONS FOR USE
Take MONZEM LC 10/5MG TABLET as advised by your physician. Swallow MONZEM LC 10/5MG TABLET with alass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of MONZEM LC 10/5MG TABLET for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF MONZEM LC 10/5MG TABLET

COMMON

Upper respiratory infection

Cough, cold, fever or flu-like symptoms

Pharyngitis (inflammation of the pharynx)

Headache and tiredness

Dizziness, sleepiness

Nausea, vomiting, dry mouth, thirst, stomach pain, diarrhoea, indigestion

Otitis media (inflammation or infection of the ears)

Skin rash

Bleeding from the nose

Muscle pain, joint pain

UNCOMMON

Exhaustion

Behaviour and mood-related changes

Agitation including aggressive behaviour or hostility

Seizures

Dream abnormalities

Restlessness

Drowsiness

Bruising, itching, hives

Muscle pain, muscle cramps, weakness

Feeling unwell, swelling

RARE

Increased bleeding tendency

Uncontrolled muscle movements

Angioedema (swelling underneath the skin)

Palpitations (fast heartbeat)
Stopiving MONZEM LC 10/5MG TABLET to your child and contact doctor immediately if your child experiences any of the following side effects:
Severe allergic reactions (such as skin rash, itching, swelling of the face, eyelids, mouth, throat and neck and difficulty in breathing or swallowing)

Systemic eosinophilia (increased levels of WBC in the blood)

Vasculitis or Churg-Strauss syndrome (inflammation of the blood vessels)

Neuropsychiatric disorders (such as agitation, anxiety, depression, disorientation, hyperactivity, nightmares, hallucinations, insomnia, memory impairment, walking in sleep, tremor, attention disturbance)

Thoughts of harming or killing yourself (suicidal ideation)

HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Try to take MONZEM LC 10/5MG TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Diarrhoea:
Drink lots of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own to treat diarrhoea. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
Try to rest and relax.et enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS

PREGNANCY
MONZEM LC 10/5MG TABLET should be used with caution during pregnancy only if considered clearly necessary. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
BREASTFEEDING
MONZEM LC 10/5MG TABLET should be used with caution in breast-feeding. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience sleepiness/drowsiness, fatigue or physical weakness. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking MONZEM LC 10/5MG TABLET as it could cause a reduction in alertness and impairment of performance. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
KIDNEY
MONZEM LC 10/5MG TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
LUNGS
MONZEM LC 10/5MG TABLET is not recommended for use in patients with asthma attacks. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
OTHERS
MONZEM LC 10/5MG TABLET is not recommended for use if you:
Havealactose intolerance (inherited condition in which the body cannot convertalactose tolucose)

Have Lapp lactase deficiency (deficiency of the enzyme lactase in the body)

Havelucose-galactose malabsorption

Have phenylketonuria (release of phenylalanine in urine)
Before taking MONZEM LC 10/5MG TABLET, inform your physician if you:
Have or at risk of having epilepsy

Have scheduled allergy skin tests

Have sensitivity to aspirin or other NSAIDs

Have any predisposing factors of urinary retention (Ex. spinal cord lesion, prostatic hyperplasia)
Use in pediatrics:
MONZEM LC 10/5MG TABLET is strictly not recommended for use in infants and children (aged below 15 years). Consult your child?s doctor for advice.
Use ineriatrics:
MONZEM LC 10/5MG TABLET should be used with caution in elderly patients (aged 65 years or above). Proper dose titrations and careful monitoring of kidney functions are required in such patients. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Before taking MONZEM LC 10/5MG TABLET, inform your doctor, if you are taking any of the following medicines:
Gemfibrozil?(used to control high blood cholesterol levels)

CNS depressants (Ex. phenobarbital), phenytoin (used to treat epilepsy)

Rifampicin (used to treat tuberculosis)

Ritonavir (a medicine used to treat viral infections)

Theophylline (a medicine used to treat asthma)
Overdosage:
If you or anyone else take too much of MONZEM LC 10/5MG TABLET, contact your doctor immediately oro to a hospital straight away. Overdosage symptoms of MONZEM LC 10/5MG TABLET might include stomach pain, thirst, sleepiness, headache, vomiting, hyperactivity, agitation, excitation and restlessness.
SYNOPSIS

Drug :?? Levocetirizine, Montelukast

Pharmacological Category :?? H1 receptor antagonist, Leukotriene receptor antagonist

Therapeutic Indication :?? Allergic rhinitis, Bronchial asthma, Chronic idiopathic urticaria

Dosage Forms :?? Tablet, Capsule, Dispersible Tablet, Oral Solution, Syrup, Suspension

MORE INFORMATION

Keep MONZEM LC 10/5MG TABLET out of reach of children

Store MONZEM LC 10/5MG TABLET at room temperature

FAQs ABOUT MONZEM LC 10/5MG TABLET
How long does it take for MONZEM LC 10/5MG TABLET to provide relief from symptoms?
Following oral administration with MONZEM LC 10/5MG TABLET, it is believed to provide relief from the symptoms of allergy and asthma within 30 minutes to an hour. Please note that the onset of action varies from product to product and consult your doctor if you have any queries.
Can MONZEM LC 10/5MG TABLET be used to treat acute asthma attacks?
No, MONZEM LC 10/5MG TABLET is used only to prevent asthma attacks. MONZEM LC 10/5MG TABLET should not be used on an asthma attack that has been started already. Contact your doctor oro to the nearby hospital to avoid exacerbation of the attack.
Can MONZEM LC 10/5MG TABLET be used in infants?
No, MONZEM LC 10/5MG TABLET is only meant to be used in adults and in adolescents (aged 15 years or above). MONZEM LC 10/5MG TABLET is strictly not recommended for use in children aged between 6 months to 11 years of age without consulting your doctor.
Can MONZEM LC 10/5MG TABLET make you feel sleepy?
Yes, MONZEM LC 10/5MG TABLET may make you feel sleepy or drowsy. Try to rest and relax.et enough sleep. Avoid driving or operating any tools or machines while you are feeling sleepy. Avoid alcohol intake, as it could aggravate your existing condition. Consult your doctor if the symptom did not improve.
Is MONZEM LC 10/5MG TABLET safe to use in patients with kidney problems?
MONZEM LC 10/5MG TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease. Consult your doctor before taking MONZEM LC 10/5MG TABLET.
REFERENCES
1. KD. Tripathi. Histamines and Antihistamines & Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page ? 166-168 & 228-229.
2. Peter J. Barnes. Pulmonary pharmacology. Randal A. Skidgel, Allen P. Kaplan and Ervin. Erdos. Histamine, Bradykinin, and their antagonists.oodman &ilman?s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page ? 918-923 & 1052-1054.
3.erald. Briggs and Roger K. Freeman. L & M. A referenceuide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page ? 2219-2220 & 2629-2632.
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5. S M Adsule,?D Misra. Long term treatment with montelukast and levocetirizine combination in persistent allergic rhinitis: review of recent evidence. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. [Revised in June 2010] [Accessed on 13th October 2021] https://pubmed.ncbi.nlm.nih.gov/21121394/
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7. E Nettis,?G F Calogiuri,?E Di Leo,?F Cardinale,?L Macchia,?A Ferrannini,?and?A Vacca. Once daily levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria. NCBI; PMC US National Library of Medicine, National Institute of Health. 2009. [Accessed on 13th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048603/
8. TusharKanti Sarkar. Effectiveness and safety of levocetirizine 10 mg versus a combination of levocetirizine 5 mg and montelukast 10 mg in chronic urticaria resistant to levocetirizine 5 mg: A double-blind, randomized, controlled trial. ResearchGate. Indian Journal of Dermatology, Venereology and Leprology. June 2017. [Accessed on 13th October 2021] https://www.researchgate.net/publication/317945813_Effectiveness_and_safety_of_levocetirizine_10_mg_versus_a_combination_of_levocetirizine_5_mg_and_montelukast_10_mg_in_chronic_urticaria_resistant_to_levocetirizine_5_mg_A_double-blind_randomized_contr
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USEFUL DIAGNOSTIC TESTS

Complete Blood Count

VIDEOS

Levocetirizine Montelukast TABLET ? Drug Information
Levocetirizine Montelukast TABLET : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
PRODUCT DETAILS

Net Qty

1 N

Shelf Life

24 months

Item Weight

17.5

Ingredient

LEVOCETIRIZINE 5MG MONTELUKAST 10MG

Hsn Code

30049099

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