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Dermovate-Nn Ointment SpecificationRequires Prescription (YES/NO)YesGenericsClobetasol Propionate , Neomycin Sulphate , Nystain Used ForEczemaHow it worksClobetasol propionate is a highly active corticosteroid with topical anti-inflammatory activity. The major effect of clobetasol propionate on skin is a non-specific anti-inflammatory response, partially due to vasoconstriction and decrease in collagen synthesis.The use of nystatin in the local treatment of candidal infections of the skin and of neomycin as a broad-spectrum antibiotic is well known.The principle action of the preparation is based on the anti-inflammatory activity of the corticosteroid. The broad spectrum antibacterial and anti-candidal activity provided by the combination of neomycin and nystatin allow this effect to be utilized in the treatment of condition which are or are likely to become infected.Dermovate-Nn Ointment Usage And SafetyDosageClobetasol Propionate , Neomycin Sulphate , Nystain Side EffectsCommon (may affect up to 1 in 10 people) : Veins under the surface of your skin may become more noticeable - Thinning of your skinUncommon (may affect up to 1 in 100 people) : Stretch marks may developVery rare (may affect up to 1 in 10,000 people) : An increased risk of infection - An allergic skin reaction where the ointment is applied - A feeling of burning, pain, irritation or itching where the ointment is applied- Rash, itchy bumpy skin or redness of the skin - Thinning and dryness of your skin and it may also damage or wrinkle more easily - An increase or reduction in hair growth or hair loss and changes in skin colour- Weight gain, rounding of the face - Delayed weight gain or slowing of growth in children - Bones can become thin, weak and break easily - Cloudy lens in the eye (cataract) or increased pressure in the eye (glaucoma)- Increased blood sugar levels or sugar in the urine - High blood pressure. Drug InteractionsCYP3A4 inhibitors (e.g. ritonavir and itraconazole) , Systemic aminoglycoside therapy , Neuromuscular blocking agents.IndicationThis medicine is used to help reduce the redness and itchiness of certain skin problems. These skin problems include eczema or psoriasis, where an infection may be a problem. When not to UseDo not use Clobetasol/neomycin/nystatin Ointment: - if you are allergic to clobetasol propionate, neomycin sulfate, nystatin or any of the other ingredients of this medicine- On a child under 2 years old - to treat any of the following skin problems, it could make them worse : - Acne - severe flushing of skin on and around your nose (rosacea) - spotty red rash around your mouth (perioral dermatitis) - itching around your back passage or private parts - unless your doctor has told you to do so - viral infections, such as cold sores, herpes or chicken pox - fungal infections, such as ringworm, athletes foot or thrush - skin blisters or sores that are caused by an infection - outer ear infections when the ear drum is perforated. Dermovate-Nn Ointment PrecautionsPrecautionPseudomembranous colitis has been reported with the use of antibiotics and may range in severity from mild to life-threatening. Therefore, it is important to consider its diagnosis in patients who develop diarrhoea during or after antibiotic use. Although this is less likely to occur with topically applied neomycin, if prolonged or significant diarrhoea occurs or the patient experiences abdominal cramps, treatment should be discontinued immediately, and the patient investigated further.Dermovate-Nn Ointment WarningsWarning 1Local hypersensitivity reactions may resemble symptoms of the condition under treatment . If signs of hypersensitivity appear, application should be stopped immediately.Warning 2Application to the face is undesirable as, more than other areas of the body, this area may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. If used on the face, treatment should be limited to only a few days. This must be borne in mind when treating such conditions as psoriasis and severe eczema.Warning 3If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as cataract and glaucoma might result from repeated exposure. If the ointment does enter the eye, the affected eye should be bathed in copious amounts of water.Dermovate-Nn Ointment Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.