MELANORM MS Cream 15gm Allschoolabs -

Specification

INTRODUCTION
MELANORM MS CREAM is a combination of Hydroquinone, Tretinoin, Mometasone furoate which belongs to the group of medicines called Depigmenting agents, Retinoids and Corticosteroids respectively. It is used in adults for the treatment of moderate to severe melasma (dark spots on the skin) in association with sun-avoidance measures, like using sunscreens and wearing protective clothing.
Melasma is one of the most frequently acquired hyperpigmentation (excess melanin production) disorders with symptoms such as symmetrical brown patches on sun exposed areas mainly on face.
It is advised to avoid exposure to sun during treatment with MELANORM MS CREAM for better results. While going out apply sunscreens and wear full covering protective clothes.
Before using MELANORM MS CREAM inform your doctor if you have any liver, kidney, lung or heart diseases.
Safety and efficacy of MELANORM MS CREAM is not established in pregnant women and in children below 12 years of age. Ask for your doctor?s advice before using. MELANORM MS CREAM should be used with caution in breastfeeding women.
The most common side effects of using MELANORM MS CREAM are mild burning, stinging, redness and dryness. Consult your doctor if any of the symptoms worsen or doesn?t improve.
USES OF MELANORM MS CREAM
It is used in adults to
Treats moderate to severe melasma (dark spots on the skin)

HOW MELANORM MS CREAM WORKS
MELANORM MS CREAM helps in treating melasma where Hydroquinone is a skin bleaching agent that blocks enzyme tyrosinase which is responsible for the production of melanin that cause pigmentation. Thus, it helps for fading of dark spots in skin. Tretinoin helps to recover the damage to the skin caused by sun exposure (photodamage) by thickening skin layer and loss of keratinized cells.it helps to rejuvenate the skin. Mometasone furoate blocks prostaglandin synthesis and reduces redness, swelling and itching caused by tretinoin and other skin infections.
DIRECTIONS FOR USE
Apply MELANORM MS CREAM as advised by your physician. It is for external use only. Wash your hands before and after applying MELANORM MS CREAM. Wash your face with a mild soap and dry properly. Apply MELANORM MS CREAM at night and gently massage it in until it is absorbed. Avoid contact with your eyes, nose, mouth, mucous membrane. Avoid exposure to sunlight while using this medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF MELANORM MS CREAM

COMMON

Mild burning

Stinging

Redness

Dryness

RARE
Stop using MELANORM MS CREAM and consult your doctor immediately if you experience any of the following:
Infraorbital and paranasal fissures

HOW TO MANAGE SIDE EFFECTS
Dry skin:
Drink plenty of water, milk, honey and stay hydrated. Apply sunflower oil, coconut oil ,aloe vera or petroleum jelly to moisturize skin. Contact doctor if it doesn?t improve.
Burning sensation:
Apply cool compress or wet cloth over affected area. Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin and apply calamine lotion as a coolant. Contact doctor if it is not subsiding.
WARNING & PRECAUTIONS

PREGNANCY
The safety and efficacy of MELANORM MS CREAM is not being established in pregnant women. Consult with your doctor before using.
BREASTFEEDING
MELANORM MS CREAM should be used with caution in breast feeding women. Consult with your doctor before using.
ALLERGY
Do not use MELANORM MS CREAM if you are allergic to Hydroquinone, Tretinoin, Mometasone or any other constituents of this medicine. Consult your doctor before using.
OTHERS
Use in paediatrics:
The safety and efficacy of MELANORM MS CREAM is not being established in children below 12 years of age. Consult with your child?s doctor before using it for your child.
Use in geriatrics:
There is no information on the use of MELANORM MS CREAM in elderly patients. Consult your doctor before using MELANORM MS CREAM.
INTERACTIONS
A. Drug ? drug interactions:
Before using MELANORM MS CREAM, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.
Overdosage:
If you or anyone else accidentally ingests or apply too much of MELANORM MS CREAM, consult your doctor immediately.
SYNOPSIS

Drug :?? Hydroquinone, Tretinoin, Mometasone

Pharmacological Category :?? Hypopigmenting agents, Retinoids, Corticosteroids

Therapeutic Indication :?? Melasma

Dosage Forms :?? Cream, Gel, Ointment, Soap

MORE INFORMATION

Keep MELANORM MS CREAM out of reach of children

Store MELANORM MS CREAM at room temperature not exceeding 25?C

FAQs ABOUT MELANORM MS CREAM
What is MELANORM MS CREAM used for?
MELANORM MS CREAM is used in adults for the treatment of moderate to severe melasma (dark spots on the skin) in association with sun-avoidance measures, like using sunscreens and wearing protective clothing. Consult doctor before using.
How to use MELANORM MS CREAM?
Apply MELANORM MS CREAM as advised by your physician. It is for external use only. Wash your hands before and after applying MELANORM MS CREAM. Wash your face with a mild soap and dry properly and gently massage the medicine until it is absorbed. Avoid contact with your eyes, nose, mouth, mucous membrane. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Can I use MELANORM MS CREAM to treat wounds?
MELANORM MS CREAM is not recommended to use on wounds and ?ulcerated skin . Consult doctor before using MELANORM MS CREAM.
Do I need to take any precaution while using MELANORM MS CREAM?
It is advised to reduce exposure to sun during treatment with MELANORM MS CREAM for better results. While going out apply sunscreens and wear full covering protective clothes. Exposure to sunlight or ultra-violet light will cause repigmentation of lightened skin. Do not apply MELANORM MS CREAM to broken skin.
What is the best time to use MELANORM MS CREAM?
It is advised to use MELANORM MS CREAM before bedtime. This will reduce the chances of exposure of the treated skin to sun. However, ask for your doctor?s advice before using.
REFERENCES
1. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of Medical Pharmacology. Eighth Edition, 2019. Page ? 952, 953, 955.
2.?Kiran V Godse. Triple combination of hydroquinone, tretinoin and mometasone furoate with glycolic acid peels in melasma. NIH National Library of Medicine, National Centre for Biotechnology. Pubmed Central. Jan 2009. [Accessed on 15th September 2022]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800888/
3.?Kowichi Jimbow, HirokoObata, Madhu A.Pathak, Thomas B.Fitzpatrick. Mechanism of depigmentation by hydroquinone. Journal of investigative dermatology. Science Direct. January 2016. [Accessed on 15th September 2022]?https://www.sciencedirect.com/science/article/pii/S0022202X15442642
4. Torrent Pharmaceuticals Ltd. Aurochem Laboratorie. Lookbrite (Hydroquinone Tretinoin Mometasone) [Accessed on 15th September 2022]?https://www.torrentian.com/pisheet/Upload/PI_Sheet/2476.pdf
5. Torque pharma. No Scars (Hydroquinone Tretinoin Mometasone). [Accessed on 15th September 2022]?https://www.torquepharma.com/no-scars-cream/
6. Leeford Healthcare. Ultrabrite Cream (Hydroquinone Tretinoin Mometasone). [Accessed on 15th September 2022]?https://www.leeford.in/product/1346/ultrabrite-cream-15-g
7. Leeford Healthcare. Elosone HT Forte (Hydroquinone Tretinoin Mometasone). [Accessed on 15th September 2022]?https://www.leeford.in/product/1459/elosone-ht-forte
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