Arthrotec contain diclofenac and misoprostol. It contains diclofenac which is a NSAID that reduces fever and relief pain and inflammatory conditions like rheumatoid arthritis and osteoarthritis. This combination is a safe alternative for patients who have ulcer due to the presence of misoprostol which protects the gastric lining. take this medication with food to reduce the likelihood of gastric irritation and diarrhoea.