Benzyl Penicillin Injection 1 MIU 10 Vial works by weakening the cell walls of bacteria. It allows holes to appear in the cell walls, which kills off the bacteria causing the infection.
Side effects
Major & minor side effects for Benzyl Penicillin Injection 1 MIU 10 Vial

Chills and fever

Fatigue

Headache

Low blood pressure

Fast heart rate

Nausea and Vomiting

Diarrhea

Blurred vision rare

Shortness of breath

Blood in stools

Uses of Benzyl Penicillin Injection 1 MIU 10 Vial
What is it prescribed for?

Upper Respiratory Tract Infection
This medicine is used to treat mild to moderate infections of the upper respiratory tract due to susceptible streptococcus species.

Syphilis
This medicine is used to treat syphilis, a sexually transmitted infection caused by the bacteria Treponema pallidum.

Prophylaxis for Rheumatic Fever
This medicine is used for the prophylactic management of rheumatic fever.

Concerns

Frequently asked questions

Onset of action
The amount of time required for this medicine to show its action is not clinically established.

Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to benzathine penicillin G, any other antibiotic of the penicillin or any other inactive ingredients present along with it.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

General Warnings

Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Kidney impairment
This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Clostridium difficile-associated diarrhea
Discontinue the use of this medicine as per the doctor’s instructions if severe diarrhea occurs after receiving this medicine. This medicine may cause an imbalance in the microbial flora of the large intestine, decreasing the gut-friendly bacteria and promoting the growth of a bacteria called Clostridium difficile, resulting in severe diarrhea.

Driving or Operating machinery
Use of this medicine may cause symptoms such as blurred vision, confusion, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Hypersensitivity reactions
This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Route of administration
This medicine is recommended for deep intramuscular administration only. Do not administer this medicine into or near an artery or nerve due to the risk of severe adverse effects.This medicine is recommended for deep intramuscular administration only. Do not administer this medicine into or near an artery or nerve due to the risk of severe adverse effects.

Dosage

Missed Dose
Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low. If you miss any scheduled dosing of this medicine, contact your doctor immediately for further instructions.

Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Live cholera vaccine severe

Methotrexate severe

Tetracycline moderate

Ethinyl Estradiol moderate

Warfarin moderate

Disease interactions

severe
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient’s condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

General Instructions

This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines including herbs and supplements as well as all your medical conditions before receiving this medicine. Report any undesired side effects to the doctor.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

References

netdoctor.co.uk –
Benzylpenicillin [Internet].
Available from: https://www.netdoctor.co.uk/medicines/infection/a6484/crystapen-benzylpenicillin/
[cited 20/7/2020].
2020