Nebcin Injection 20 mg 1 Ampx1 mL is a broad-spectrum antibiotic which kills the bacteria by blocking the production of certain proteins that are required for their growth.
Side effects
Major & minor side effects for Nebcin Injection 20 mg 1 Ampx1 mL

Neuromuscular blockade severe

Hearing loss

Ringing or buzzing in the ears

Headache

Nosebleed severe

Difficulty in breathing severe

Hoarseness of voice severe

Unusual tiredness and weakness severe

Fever severe

Uses of Nebcin Injection 20 mg 1 Ampx1 mL
What is it prescribed for?

Bacterial infections
Nebcin Injection 20 mg 1 Ampx1 mL injection is used in the treatment of bacterial infections of the abdomen, brain and spinal cord, heart, bones, and joints.

Cystic fibrosis
Nebcin Injection 20 mg 1 Ampx1 mL is used as an injection and an intranasal agent for the treatment of cystic fibrosis. The symptoms of this disease are clubbing of fingers, breathing difficulty, poor growth, frequent chest infection, poor weight gain, and coagulation disorder in a few patients, and infertility in males.

Concerns

Frequently asked questions

Onset of action
The amount of time required for this medicine to show its action is not clinically established.

Duration of Effect
The effect of this medicine lasts for an average duration of 6 to 24 hours depending on the route of administration.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Eye drops or ear drops of this medicine may be used since they present little or no risk to the nursing infant. Discuss all the risks and benefits with your doctor before taking this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Nebcin Injection 20 mg 1 Ampx1 mL or other aminoglycosides.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Eye drops or ear drops of this medicine may be used since they present little or no risk to the nursing infant. Discuss all the risks and benefits with your doctor before taking this medicine.

General Warnings

Drug resistance
Use of Nebcin Injection 20 mg 1 Ampx1 mL without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Neuromuscular disorders
Nebcin Injection 20 mg 1 Ampx1 mL is not recommended for use in patients with existing neuromuscular diseases like Parkinsonism or Myasthenia gravis since it may worsen the condition of the patient.

Impaired kidney function
Nebcin Injection 20 mg 1 Ampx1 mL may increase the risk of kidney injury, especially when high doses are used for a prolonged period of time. Suitable dose adjustments should be made based on the creatinine clearance (CrCl).

Dosage

Missed Dose
If a dose is missed, take the dose as soon as you remember it. If it is almost the time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Colistin severe

Diuretics severe

Live cholera vaccine severe

Neuromuscular blockers severe

Disease interactions

severe
Consume an adequate amount of water to prevent kidney injury and hearing problems. Fluid status should be monitored closely, especially in patients with severe diarrhea and vomiting who are receiving Nebcin Injection 20 mg 1 Ampx1 mL. Frequent monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments should be made based on the clinical condition of the patient.

General Instructions

Strictly follow the instructions on the label and take Nebcin Injection 20 mg 1 Ampx1 mL only as directed. Drink plenty of water to avoid kidney damage. Do not take more than what is prescribed or share this medication with other people. It is advised that you inform the doctor about all the medicines or herbal products that you are using and about all your medical conditions before taking this medicine.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

References

practo.com –
Tobramycin [Internet].
Available from: https://www.practo.com/medicine-info/tobramycin-566-api
[cited 10 october 2019].
1 Aug 2017

medlineplus.gov –
Tobramycin [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a681003.html
[cited 10 october 2019].
01 October 2019

dailymed.nlm.nih.gov –
Tobramycin [Internet].
Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a384641c-04e3-4ab5-b152-7408cd07b64d&audience=consumer
[cited 10 october 2019].
April 23, 2015