Intalfa 3Miu Penfill Injection 1?s Allschoolabs -

Description

INTRODUCTION
INTALFA 3MIU PENFILL contains Interferon alpha 2B which belongs to a group of medicines called immunomodulators. It is used to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, condylomata acuminata, AIDS-related Kaposi?s sarcoma, chronic hepatitis B and C. Hairy cell leukemia produces abnormal white blood cells that travel to the spleen where they trap and destroy normal blood cells.
Interferons are low molecular glycoprotein cytokines produced by host cells in response to viral infections. Interferon alpha 2B interacts with receptors on the surface of cells, where it fights with cancer, directly by interfering with the cancer cells ability to divide, and indirectly by modifying the body?s response to the cancer cells.
Before receiving INTALFA 3MIU PENFILL, tell your physician if you have liver, kidney or heart problems, are pregnant or breastfeeding. This medicine is not suitable for use in children and adolescents below 18 years of age. The common side effects are tiredness, nausea, diarrhoea and headache.
USES OF INTALFA 3MIU PENFILL
Treats,
Hairy cell leukemia

Malignant melanoma

Follicular lymphoma

Condylomata acuminata

AIDS-related Kaposi?s sarcoma

Chronic hepatitis B and C

HOW INTALFA 3MIU PENFILL WORKS
Interferon alpha interacts with receptors on the surface of cells, where it fights cancer; directly by interfering with the cancer cells ability to divide, and indirectly by modifying the body?s response to the cancer cells.
DIRECTIONS FOR USE
INTALFA 3MIU PENFILL will be administered by your doctor or nurse as subcutaneous (under the skin) or intramuscular injection.
SIDE EFFECTS OF INTALFA 3MIU PENFILL

SERIOUS

Mental health problems

Heart or blood problems

Depression

Severe chest pain

Trouble breathing

Change in vision

Unusual bleeding

High fever

Stomach pain

COMMON

Flu-like symptoms

Extreme fatigue (tiredness)

Nausea

Taste changes

Diarrhea

Loss of appetite

Blood sugar problems

Thyroid problems

Rash, dry or itchy skin, redness and swelling (at application site)

Trouble sleeping and headaches

HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.
Nausea:
Take normal regular meals and do not eat spicy foods.
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.
WARNING & PRECAUTIONS

PREGNANCY
INTALFA 3MIU PENFILL is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
INTALFA 3MIU PENFILL is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or handle any machines while taking this medicine as it may cause less alertness.
KIDNEY
INTALFA 3MIU PENFILL should be used with caution in patients suffering from kidney diseases. Consult your doctor for advice.
LIVER
INTALFA 3MIU PENFILL is not recommended in patients with decompensated liver diseases. Consult your doctor for advice.
ALLERGY
Tell your doctor if you are allergic (hypersensitive) to interferon alpha 2B.
HEART DISEASE
INTALFA 3MIU PENFILL should be used with caution if you are suffering from heart attack or heart problems. Consult your doctor for advice.
OTHERS
Tell your doctor before taking this medicine if you have or had:
Autoimmune hepatitis

Depression or anxiety

Autoimmune disease

Blood disorders

Thyroid disorders

Psychiatric disorders

Ophthalmologic disorders

INTERACTIONS
Tell your doctor if you are taking or recently used medicines or the following,
Theophylline (treats breathing problem)

Zidovudine

SYNOPSIS

Drug :?? Interferon Alpha 2B

Pharmacological Category :?? Immunomodulators

Therapeutic Indication :?? Hairy cell leukemia, Malignant melanoma, Follicular lymphoma,?Condylomata acuminata, AIDS-related Kaposi?s sarcoma,?Chronic hepatitis B and C

Dosage Forms :?? Injection

MORE INFORMATION

Keep out of reach of children

Store at 2 ? 8?C

FAQs ABOUT INTALFA 3MIU PENFILL
Can I take INTALFA 3MIU PENFILL if I have liver problems?
It is not recommended for use if you have decompensated liver disease. Consult your doctor for advice.
Does INTALFA 3MIU PENFILL safe during pregnancy?
No, it is not recommended for use during pregnancy. Consult your doctor for advice.
What are the side effects of INTALFA 3MIU PENFILL?
The common side effects are tiredness, nausea, diarrhoea and headache.
REFERENCES
1. KD Tripathi MD. Antimicrobial drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page ? 804.
2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page ??723-25.
3. Franciane Paul, Sandra Pellegrini, and Gilles Uz?. IFNA2: The prototypic human alpha interferon. May 14, 2015. [Accessed on June 18, 2021]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629289/
4. MERCK & CO. INC., U.S. Food & Drug Administration. [Revised on Aug, 2014] [Accessed on June 18, 2021]?https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/103132s5190lbl.pdf
5. Merck Sharp & Dohme Corp. [Revised on Feb, 2016] [Accessed on June 18, 2021]?https://www.merck.com/product/usa/pi_circulars/i/intron_a/intron_a_pi.pdf
USEFUL DIAGNOSTIC TESTS

Albumin/Globulin Ratio, Serum

Bilirubin Total

Calcium

Complete Blood Count

Hepatitis B (Core) IgM Antibody

Hepatitis B s (Surface) Antigen

Hepatitis C Virus Total Antibody

Kidney Function Test

Liver Function Test

Peripheral Smear Examination

PRODUCT DETAILS

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