CADIQUIS 5 Tablet 10?s Allschoolabs -

Description

INTRODUCTION
CADIQUIS 5 TABLET contains Apixaban, which belongs to theroup of medicines called Anticoagulants. It is used to prevent blood clots in patients with an irregular heartbeat (atrial fibrillation). These blood clots can dislodge and travel throughout the body, resulting in systemic embolism and stroke.
CADIQUIS 5 TABLET also helps in the treatment of blood clots in the legs (deep vein thrombosis) and the veins of the lungs (pulmonary embolism) and in the prevention of their recurrence in either legs or lungs.
CADIQUIS 5 TABLET should be taken with caution in patients who have liver or kidney disease. CADIQUIS 5 TABLET is contraindicated in patients who have active bleeding or have a disease that can lead to active bleeding, such as an active ulcer or a recent bleed in the brain.
CADIQUIS 5 TABLET should be used with caution during pregnancy or breastfeeding. CADIQUIS 5 TABLET is not recommended for use by children and adolescents (under the age of 18). CADIQUIS 5 TABLET should be used with caution in elderly patients over the age of 80.
The most common side effects of taking CADIQUIS 5 TABLET are bleeding (eyes, nose,ums, urine, rectum, stomach or bowel), bruising or swelling, anaemia, low blood pressure and a quickened heart rate. If any of these symptoms worsen, contact your doctor immediately.
USES OF CADIQUIS 5 TABLET

Treats blood clots formed in the legs (deep vein thrombosis) and blood clots formed in the veins of the lungs (pulmonary embolism)

Prevents the forming of blood clots in heart patients with an irregular heartbeat (atrial fibrillation)

HOW CADIQUIS 5 TABLET WORKS
CADIQUIS 5 TABLET helps to prevent the formation of blood clots by acting on the blood clotting mechanism of the body. It blocks clotting factor Xa which is an essential factor in the clotting mechanism.
DIRECTIONS FOR USE
Take CADIQUIS 5 TABLET as advised by your physician. Swallow the medicine with alass of water. If you have difficulty swallowing the tablet as a whole, talk to your doctor about other ways to take CADIQUIS 5 TABLET. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF CADIQUIS 5 TABLET

COMMON

Bleeding affecting (eyes, stomach or bowel, rectum, blood in the urine, nose andums)

Bruising and swelling

Anaemia which may lead to tiredness or paleness

Low blood pressure (faint or have a quickened heartbeat)

Nausea

UNCOMMON

Bleeding in the brain or spinal column, in the mouth or blood in spit when coughing, into the abdomen, from the vagina

Bright/red blood in the stools

Bleeding occurring after the operation including bruising and swelling

Leaking of blood/liquid from the surgical wound/incision (wound secretion) or injection site

Bleeding from a haemorrhoid

Reduced count of platelets in your blood

Yellowing of the skin and eyes

Skin rash

Itching

Hair loss

RARE

Bleeding in the lungs or your throat, into the space behind the abdominal cavity, into a muscle

Skin rash forming blisters and looks like small targets (dark spots in the centre surrounded by a paler area, with a dark ring around the edge) (erythema multiforme)
Stop taking CADIQUIS 5 TABLET and contact your doctor immediately if you experience any of the following side effects:
Severe allergic reaction (hypersensitivity) causing swelling of lips, mouth, tongue and throat

Breathing difficulties

HOW TO MANAGE SIDE EFFECTS
Nausea:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.
WARNING & PRECAUTIONS

PREGNANCY
The effects of CADIQUIS 5 TABLET on pregnancy and the unborn child are not known, hence it is not recommended to take it during pregnancy. Consult your doctor before taking it.
BREASTFEEDING
It is not known if CADIQUIS 5 TABLET passes into human breast milk. Consult your doctor before taking this medicine while breastfeeding.
DRIVING AND USING MACHINES
CADIQUIS 5 TABLET does not impair the ability to drive or use machines. Consult your doctor.
KIDNEY
CADIQUIS 5 TABLET should be taken with caution in patients with severe kidney disease or who are on dialysis. Consult your doctor before taking it.
LIVER
CADIQUIS 5 TABLET is not recommended for use in patients having liver diseases such as hepatic coagulopathy. It should be used with caution in patients with liver problems or a history of liver problems. Consult your doctor before taking it.
ALLERGY
Do not take CADIQUIS 5 TABLET if you are allergic to Apixaban.
HEART DISEASE
CADIQUIS 5 TABLET should be taken with caution in patients with prosthetic heart valves. Consult your doctor before taking it.
OTHERS
Before taking CADIQUIS 5 TABLET, inform your doctor if you:
Have bleeding disorders

Have very high blood pressure

Have antiphospholipid syndrome (a disorder of the immune system that increases the risk of blood clots)

Have to undergo surgery which will cause bleeding

Have lactose intolerance
Use in pediatrics:
CADIQUIS 5 TABLET isenerally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking it.
?Use ineriatrics:
CADIQUIS 5 TABLET should be used with caution in elderly patients (aged above 80 years). Consult your doctor before taking it.

INTERACTIONS
A. Drug?Drug Interactions:
Medicines for fungal infections (Ex. ketoconazole)

Antiviral medicines for HIV / AIDS (Ex. ritonavir)

Other medicines that are used to reduce blood clotting (Ex. enoxaparin)

Anti-inflammatory or pain-relieving medicines (Ex. acetylsalicylic acid, naproxen)

Medicines for high blood pressure or heart problems (Ex. diltiazem)

Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors (used in the treatment of depression) (Ex. escitalopram)

Medicines to prevent epilepsy or seizures (Ex. phenytoin, etc.)

St John?s Wort (herbal supplement used in the treatment of depression)

Medicines to treat tuberculosis or other infections (Ex. rifampicin)
Overdosage:
If you or anyone else accidentally take too much of CADIQUIS 5 TABLET, consult your doctor immediately or visit the nearby hospital. Overdose of CADIQUIS 5 TABLET can result in increased bleeding.
SYNOPSIS

Drug :?? Apixaban

Pharmacological Category :?? Anti-coagulants

Therapeutic Indication :?? Prevention of blood clots in atrial fibrillation, Deep vein thrombosis, Pulmonary embolism

Dosage Forms :?? Tablet

MORE INFORMATION

Keep CADIQUIS 5 TABLET out of reach of children

Store below 30?C

FAQs ABOUT CADIQUIS 5 TABLET
Is CADIQUIS 5 TABLET a blood thinner?
Yes. [GBKEYWORD] is a blood thinner, also called an anticoagulant. It prevents blood clot formation and makes it easier for the blood to flow through the body. CADIQUIS 5 TABLET blocks an essential factor of the clotting mechanism, thereby making it easy for the blood to flow.
What precautions should I take while taking CADIQUIS 5 TABLET?
Patients taking CADIQUIS 5 TABLET should inform their doctor about their pre-existing liver, heart or kidney disease. As CADIQUIS 5 TABLET is an anti-coagulant and helps in the prevention of blood clot formation, it is important to tell your doctor about any bleeding disorder or any active condition that can cause a bleed. Consult your doctor before taking it.
What if I forget to take a dose of CADIQUIS 5 TABLET?
Take the dose as soon as you remember, then take the next dose of CADIQUIS 5 TABLET at the usual time and then continue as normal. Consult your doctor once.
Is CADIQUIS 5 TABLET safe during pregnancy and breastfeeding?
No, CADIQUIS 5 TABLET is not recommended for use during pregnancy and breastfeeding. If you are pregnant, breastfeeding or planning to have a baby, consult your doctor before taking CADIQUIS 5 TABLET. If you become pregnant while taking CADIQUIS 5 TABLET, contact your doctor immediately.
What is CADIQUIS 5 TABLET used for?
CADIQUIS 5 TABLET is used to prevent blood clots in patients with an irregular heartbeat (atrial fibrillation). These blood clots have the potential to dislodge and travel throughout the body, resulting in systemic embolism and stroke.CADIQUIS 5 TABLET also helps in the treatment of blood clots in the legs (deep vein thrombosis) and the veins of the lungs (pulmonary embolism) and in the prevention of their recurrence in either legs or lungs.
What are the side effects of taking CADIQUIS 5 TABLET?
The most common side effects of taking CADIQUIS 5 TABLET are bleeding (eyes, nose,ums, urine, rectum, stomach or bowel), tiredness or paleness due to anaemia, low blood pressure and nausea. Consult your doctor if any of these symptomset worse.
What foods should I avoid while taking CADIQUIS 5 TABLET?
Avoid consumingrapefruits or juices as it impacts the effects of CADIQUIS 5 TABLET, which may lead to bleeding. To prevent such complications, consult your doctor before taking CADIQUIS 5 TABLET.
REFERENCES
1. Joseph T.?DiPiro, Robert L. Talbert, Cardiovascular Diseases, Pharmacotherapy: A Pathophysiologic Approach, Eighth Edition. 2011. Page ? 324.
2. Joseph P. Broderick,?Jordan B. Bonomo,?Brett M. Kissela,?Jane C. Khoury,?Charles J. Moomaw,?Kathleen Alwell, Daniel Woo, Matthew L. Flaherty, Pooja Khatri, Opeolu Adeoye, Simona Ferioli, Dawn O. Kleindorfer. Withdrawal of Antithrombotic Agents and Its Impact on Ischemic Stroke Occurrence. NIH. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. June 2011. [Accessed on 20th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166233/
3. Catalent Anagni S.R.L. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 20th April 2022]. https://www.medicines.org.uk/emc/files/pil.2878.pdf
4. Bristol-Myers Squibb Company, Pfizer Inc. Bristol Myers Squib. [Revised in September 2021] [Accessed on 20th April 2022]. https://packageinserts.bms.com/pi/pi_eliquis.pdf
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