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Elodep 10 mgElodep 10 mg is indicated in Depressive illness, Generalized anxiety disorder, Obsessive-compulsive disorder, Social anxiety disorderTheropeutic ClassSSRIs & related anti-depressant drugsPharmacologyElodep 10 mg is a selective inhibitor of serotonin (5-HT) re-uptake. The inhibition of 5-HT re-uptake is the only likely mechanism of action explaining the pharmacological and clinical effects of Elodep 10 mg. Elodep 10 mg has no or low affinity for a number of receptors including 5-HT1A, 5-HT2, DA D1 and D2 receptors, ?1-, ?2-, ?-adrenoceptors, histamine H1, muscarine cholinergic, benzodiazepine and opioid receptors.Dosage & Administration of Elodep 10 mgAdults: The initial dose of Elodep 10 mg Oxalate is 10 mg once daily. (A fixed dose trial of Elodep 10 mg Oxalate demonstrated the effectiveness of both 10 mg and 20 mg of Elodep 10 mg Oxalate, but failed to demonstrate a greater benefit of 20 mg over 10 mg.) If the dose is increased to 20 mg, this should occur after a minimum of one week.Panic disorder: Adult over 18 years, initially 5 mg once daily increased to 10 mg daily after 7 days; max. 20 mg daily; elderly initially half adult dose, lower maintenance dose may be sufficient; Social anxiety disorder: Adult over 18 years, initially 10 mg once daily adjusted after 2-4 weeks; usual dose 5-20 mg daily.Elderly: A single oral dose of 10 mg/day is the recommended dose for most elderly patients. Administered in excess recommended dose has not been yet established.Interaction of Elodep 10 mgElodep 10 mg should not be started until 2 weeks after stopping an MAOI. Conversely, an MAOI should not be started until at least a week after Elodep 10 mg or related antidepressant has been stopped.ContraindicationsConcomitant use in patients taking monoamine oxidase inhibitors (MAOIs) is contraindicated. Concomitant use in patients taking pimozide is contraindicated. Esita is contraindicated in patients with a hypersensitivity to Elodep 10 mg or citalopram or any of the inactive ingredients.Side Effects of Elodep 10 mgElodep 10 mg is well tolerated by most people. The most commonly reported side-effects of Elodep 10 mg are nausea, insomnia, problems with ejaculation, drowsiness, increased sweating and fatigue. Most of the side-effects experienced by patients taking Elodep 10 mg are mild and go away with continued treatment and usually do not cause patients to stop taking Elodep 10 mg.Pregnancy & LactationPregnancy:?The safety of Elodep 10 mg during pregnancy and lactation has not been established. Therefore, Elodep 10 mg should not be used during pregnancy unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the fetus.Nursing Mothers:?Elodep 10 mg is excreted in human milk. Elodep 10 mg should not be given to nursing mothers unless, in the opinion of the physician, the expected benefits to the patient outweigh the possible hazards to the childPrecautions & WarningsDuring marketing of Elodep 10 mg and other SSRIs and SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors), there have been spontaneous reports of adverse events occurring upon discontinuation of these drugs, particularly when abrupt, including the following: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, and hypomania. While these events are generally self-limiting, there?have been reports of serious discontinuation symptoms. Patients should be monitored for these symptoms when discontinuing treatment with Elodep 10 mg. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate.Storage ConditionsStore in a cool and dry place below 30? C. Protect from light.Use In Special PopulationsPediatric Use: Safety and effectiveness in children below the age of 18 years have not been established.Geriatric patients:?Elodep 10 mg pharmocokinetics in subjects age 65 and over were compared to younger subjects in a single and multi-dose study. No overall differences in safety or effectiveness between this group and the younger subjects was observed, but greater sensitivity of some elderly individuals ca