Fungidal-HC 15 gmFor the topical treatment of inflamed dermatoses where? infection by susceptible organisms and inflammation coexist e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that ... Read moreFor the topical treatment of inflamed dermatoses where? infection by susceptible organisms and inflammation coexist e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that associated with acne. Also for interiginous eczema including inflammatory interigo, perianal and genital dermatitis. Organisms which are?susceptible to miconazole are dermatophytes and pathogenic yeasts (e.g. Candida spp.): also many Gram-positive bacteria including many strains of Streptococcus and Staphylococcus.Theropeutic ClassHydrocortisone & Combined preparationsPharmacologyMiconazole nitrate is an imidazole antifungal agent and possesses antibacterial activity. At low concentrations, it interacts with fungal cytochrome P450 which results in inhibition of a demethylation step in the biosynthesis of ergosterol. At high concentrations, miconazole interacts with membrane lipids causing direct membrane damage which results in leakage of fungus cell constituents. It appears that fungistatic effects result from the inhibition of membrane sterol synthesis and membrane. Hydrocortisone is a naturally occurring glucocorticoid that is now prepared by chemical synthesis and its main action is to reduce the response of the skin to injury (i.e. anti-inflammatory). It also has immunosuppressant and antimitotic actions. The anti-inflammatory activity of hydrocortisone is its main therapeutic property. This is thought to be mediated by the reduction in formation, release and action of the various vasoactive chemicals release during inflammation-kinins, histamine, lysosomal enzymes, prostaglandins and the complement system. Steroids decrease membrane permeability and bind to tissue receptors. They also induce vasoconstriction, by reducing vascular permeability and reversing vascular dilation which in turn decreases serum extravasation, swelling and discomfort, including itching. Thus, they effectively reduce cellular access to inflamed sites. Corticosteroids also exhibit an antimitotic effect against human epidermal cells which may account for their effectiveness in the treatment of scaly dermatoses such as psoriasis.Dosage & Administration of Fungidal-HC 15 gmIt should be applied topically to the affected area two or three times daily. The same dosage applies to both adults and children. In infants, long term continuous topical corticosteroid therapy should be avoided. Occlusive dressing is usually only necessary in the case of nail lesions. Once the inflammatory symptoms have disappointed (after about 7 days) treatment can be continued where necessary with this cream.Dosage of Fungidal-HC 15 gmApply to the affected area as a thin film two or four times daily for 1 to 2 weeks. Rub it well with your finger until this cream fully vanished on the skin. Treatment should be continued at least one week after the disappearance of all signs and symptoms. The same dosage applies to both adults and children.Interaction of Fungidal-HC 15 gmAmphotericin antagonizes the activity of Miconazole.ContraindicationsIt is contraindicated in individuals who are hypersensitive to it or any of its components. Should not be used in pregnant mother and lactating mother without physician's advice.Side Effects of Fungidal-HC 15 gmRarely local sensitivity may occur. Long term use may decrease in the production of natural hormones by the adrenal gland.Pregnancy & LactationAdministration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.Precautions & WarningsTo be dispensed only on the prescription of a registered physician. Keep out of reach of children. Take care or consult with a physician in case of use in children and elderly people for long-term use.Storage ConditionsKeep below 30?C temperature, away from light & moisture. Keep out of the reach of children.Drug ClassesHydrocortisone & Combined preparationsMode Of ActionMiconazole is a substituted imidazole, is one of the family of azoles useful in treating the superficial candidiasis and of the skin infections dermatophytosis and pityriasis versicolor, acanthameaba, seborrhoic dermatitis. Also active against Aspergillus spp., Cryptococcus neoformans, Pseudalescheria boydii and some gram-positive bacteria including Staphylococci and Streptococci. Hydrocortisone is a naturally occurring glucocorticoid that's now prepared synthetically. Its important function is in the skin injury such as inflammation. Also it has antipruritic, antimycotic and vasoconstrictive activity.Miconazole is imidazole antifungal agents that interfere with ergosterol synthesis and therefore alters the permeability of the cell membrane of sensitive fungi. Thus causes the killing of fungi, when applied to the skin, Hydrocortisone is absorbed into the skin cells. It prevents the release of certain chemicals, which is responsible for inflammation. Thus hydrocortisone reduces inflammation.PregnancyAdministration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.
Fungidal 2%It is indicated in the treatment and prevention of fungal infections of the oropharynx and gastrointestinal tract.Theropeutic ClassAural Anti-fungal preparationsPharmacologyMiconazole is a synthetic broad spectrum anti-fungal agent and acts against pathogenic fungi including yeast and dermatophytes and gram-positive bacteria (Staphylococcus and Streptococcus spp). It acts by inhibiting membrane sterol synthesis and interfering with the permeability of the fungal cell membranes.Dosage of Fungidal 2%Oropharyngeal candidosis-
Infants 4-24 month: 1.25 ml (1/4 measuring spoon) of gel, applied 4 times day after meals.
Adult and children 2 years of age and older: 2.5 ml (1/2 measuring spoon) of gel, applied 4 times a day after meals.
Gastrointestinal tract candidosis-
Infants (4 month of age or above), children and adults who have difficulty swallowing tablets: 20 mg per kg body weight per day, in four divided doses. The daily dose should not exceed 250 mg (10 ml gel) four times day.
Administration of Fungidal 2%In case of localized lesions of the mouth, a small amount of gel may be applied 2-4 times a day directly to the affected area with a clean finger. For best results, Miconazole oral gel should be kept in contact with the affected area as long as possible. The treatment should be continued for at least a week after symptoms have disappeared. For oral candidosis, dental prosthesis should be removed at night and brushed with the gel.Interaction of Fungidal 2%Miconazole can inhibit the metabolism of drugs metabolized by the cytochrome P450-3A and P450-2C9. Miconazole oral gel should not be used during treatment with cisapride, trizolam, oral midazolam, mizolastine, quinidine, simvastatin and lovastatin.ContraindicationsMiconazole is contraindicated in patients with known hypersensitivity to the active ingredient.Side Effects of Fungidal 2%Occasionally nausea and vomiting, diarrhea with long term use and rarely allergic reactions.Pregnancy & LactationThere is no information regarding the safety of Miconazole oral gel during pregnancy. So Miconazole oral gel should be avoided in pregnant women if possible or the potential hazards should be balanced against the possible benefits. As many drugs are excreted in human milk, caution should be exercised when Miconazole is administered to a nursing woman.Precautions & WarningsIf the concomitant use of Miconazole and anticoagulant is considered, the anti-coagulant effect should be monitored and titrated. Miconazole and phenytoin plasma level should also be monitored when used concomitantly. In infants and young children, caution must be taken to ensure that the gel does not obstruct the throat.Storage Conditionskeep in a dry place away from light and heat. Keep out of the reach of children.
Stop Diabetic Capsule ₦24,490.00
Nesti Dante Luxury Gold Candle 160G ₦8,300.00
PIRFEMAC 400MG TABLET 10?S ₦5,981.25
DICORATE ER 1000MG TAB 10`S ₦3,914.00
FUR TOTAL TABLET ₦3,652.75
ATORFIT CV 20MG CAP 15`S ₦8,772.75
Tynor Thumb Spica Splint-Universal Size ₦1,850.00
Bactigras Total Antiseptic Dressing ₦14,200.00
BIOCOLLAZ AG 10GM GEL ₦1,547.00
Exforge 5/160mg Tabs x 28 ₦55,900.00
ANTREOL 1 Tablet 10?s ₦45,900.00
Stardea Fluistar Sachets 20 Sachets ₦30,552.00
CALEDOC 60K CAP 4`S ₦2,186.25
FIGOMET SR 1 TABLETS 10?S ₦788.00
CTD M 6.25/50MG TAB 10`S ₦2,341.25
Fungidal-HC 15 gmFor the topical treatment of inflamed dermatoses where? infection by susceptible organisms and inflammation coexist e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that ... Read moreFor the topical treatment of inflamed dermatoses where? infection by susceptible organisms and inflammation coexist e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that associated with acne. Also for interiginous eczema including inflammatory interigo, perianal and genital dermatitis. Organisms which are?susceptible to miconazole are dermatophytes and pathogenic yeasts (e.g. Candida spp.): also many Gram-positive bacteria including many strains of Streptococcus and Staphylococcus.Theropeutic ClassHydrocortisone & Combined preparationsPharmacologyMiconazole nitrate is an imidazole antifungal agent and possesses antibacterial activity. At low concentrations, it interacts with fungal cytochrome P450 which results in inhibition of a demethylation step in the biosynthesis of ergosterol. At high concentrations, miconazole interacts with membrane lipids causing direct membrane damage which results in leakage of fungus cell constituents. It appears that fungistatic effects result from the inhibition of membrane sterol synthesis and membrane. Hydrocortisone is a naturally occurring glucocorticoid that is now prepared by chemical synthesis and its main action is to reduce the response of the skin to injury (i.e. anti-inflammatory). It also has immunosuppressant and antimitotic actions. The anti-inflammatory activity of hydrocortisone is its main therapeutic property. This is thought to be mediated by the reduction in formation, release and action of the various vasoactive chemicals release during inflammation-kinins, histamine, lysosomal enzymes, prostaglandins and the complement system. Steroids decrease membrane permeability and bind to tissue receptors. They also induce vasoconstriction, by reducing vascular permeability and reversing vascular dilation which in turn decreases serum extravasation, swelling and discomfort, including itching. Thus, they effectively reduce cellular access to inflamed sites. Corticosteroids also exhibit an antimitotic effect against human epidermal cells which may account for their effectiveness in the treatment of scaly dermatoses such as psoriasis.Dosage & Administration of Fungidal-HC 15 gmIt should be applied topically to the affected area two or three times daily. The same dosage applies to both adults and children. In infants, long term continuous topical corticosteroid therapy should be avoided. Occlusive dressing is usually only necessary in the case of nail lesions. Once the inflammatory symptoms have disappointed (after about 7 days) treatment can be continued where necessary with this cream.Dosage of Fungidal-HC 15 gmApply to the affected area as a thin film two or four times daily for 1 to 2 weeks. Rub it well with your finger until this cream fully vanished on the skin. Treatment should be continued at least one week after the disappearance of all signs and symptoms. The same dosage applies to both adults and children.Interaction of Fungidal-HC 15 gmAmphotericin antagonizes the activity of Miconazole.ContraindicationsIt is contraindicated in individuals who are hypersensitive to it or any of its components. Should not be used in pregnant mother and lactating mother without physician's advice.Side Effects of Fungidal-HC 15 gmRarely local sensitivity may occur. Long term use may decrease in the production of natural hormones by the adrenal gland.Pregnancy & LactationAdministration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.Precautions & WarningsTo be dispensed only on the prescription of a registered physician. Keep out of reach of children. Take care or consult with a physician in case of use in children and elderly people for long-term use.Storage ConditionsKeep below 30?C temperature, away from light & moisture. Keep out of the reach of children.Drug ClassesHydrocortisone & Combined preparationsMode Of ActionMiconazole is a substituted imidazole, is one of the family of azoles useful in treating the superficial candidiasis and of the skin infections dermatophytosis and pityriasis versicolor, acanthameaba, seborrhoic dermatitis. Also active against Aspergillus spp., Cryptococcus neoformans, Pseudalescheria boydii and some gram-positive bacteria including Staphylococci and Streptococci. Hydrocortisone is a naturally occurring glucocorticoid that's now prepared synthetically. Its important function is in the skin injury such as inflammation. Also it has antipruritic, antimycotic and vasoconstrictive activity.Miconazole is imidazole antifungal agents that interfere with ergosterol synthesis and therefore alters the permeability of the cell membrane of sensitive fungi. Thus causes the killing of fungi, when applied to the skin, Hydrocortisone is absorbed into the skin cells. It prevents the release of certain chemicals, which is responsible for inflammation. Thus hydrocortisone reduces inflammation.PregnancyAdministration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.