Dysen Forte SpecificationRequires Prescription (YES/NO)YesGenericsSecnidazoleUsed ForBacterial InfectionHow it worksSecnidazole is a 5-nitroimidazole antimicrobial. 5-nitroimidazoles enter the bacterial cell as an inactive prodrug where the nitro group is reduced by bacterial enzymes to radical anions. It is believed that these radical anions interfere with bacterial DNA synthesis of susceptible isolates.Dysen Forte Usage And SafetyDosageSecnidazoleSide EffectsMost frequent side-effects: Gastrointestinal disturbances, nausea, epigastric pain, metallic taste, glossitis, and stomatitis. Occasional side-effects: Urticaria, moderate leukopenia which is reversible on treatment discontinuation. Rare side-effects: Vertigo, ataxia and motor incoordination, paresthesia, and peripheral neuropathy. With secnidazole, gastrointestinal disorders e.g. nausea, vomiting, epigastric pain, etc. have been reported in very rare cases.Drug InteractionsDisulfiram , warfarin , ethinyl estradiol plus norethindrone .IndicationIt is indicated for the treatment of bacterial vaginosis in adult women.When not to UseSecnidazole is contraindicated for those patients who are hypersensitive to imidazole derivatives.Dysen Forte PrecautionsPrecautionPrescribing secnidazole in the absence of proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria .Dysen Forte WarningsWarning 1Vulvovaginal candidiasis may occur; symptomatic vulvovaginal candidiasis may require treatment with an antifungal agent .Warning 2Carcinogenicity has been seen in mice and rats treated long term with nitroimidazole derivatives, which are structurally related to secnidazole; avoid long-term use of secnidazole .Warning 3Avoid chronic use; carcinogenicity reported in mice and rats treated chronically with nitroimidazole derivatives, structurally related to secnidazole; significance unclear . Dysen Forte Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.
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Dysen Forte SpecificationRequires Prescription (YES/NO)YesGenericsSecnidazoleUsed ForBacterial InfectionHow it worksSecnidazole is a 5-nitroimidazole antimicrobial. 5-nitroimidazoles enter the bacterial cell as an inactive prodrug where the nitro group is reduced by bacterial enzymes to radical anions. It is believed that these radical anions interfere with bacterial DNA synthesis of susceptible isolates.Dysen Forte Usage And SafetyDosageSecnidazoleSide EffectsMost frequent side-effects: Gastrointestinal disturbances, nausea, epigastric pain, metallic taste, glossitis, and stomatitis. Occasional side-effects: Urticaria, moderate leukopenia which is reversible on treatment discontinuation. Rare side-effects: Vertigo, ataxia and motor incoordination, paresthesia, and peripheral neuropathy. With secnidazole, gastrointestinal disorders e.g. nausea, vomiting, epigastric pain, etc. have been reported in very rare cases.Drug InteractionsDisulfiram , warfarin , ethinyl estradiol plus norethindrone .IndicationIt is indicated for the treatment of bacterial vaginosis in adult women.When not to UseSecnidazole is contraindicated for those patients who are hypersensitive to imidazole derivatives.Dysen Forte PrecautionsPrecautionPrescribing secnidazole in the absence of proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria .Dysen Forte WarningsWarning 1Vulvovaginal candidiasis may occur; symptomatic vulvovaginal candidiasis may require treatment with an antifungal agent .Warning 2Carcinogenicity has been seen in mice and rats treated long term with nitroimidazole derivatives, which are structurally related to secnidazole; avoid long-term use of secnidazole .Warning 3Avoid chronic use; carcinogenicity reported in mice and rats treated chronically with nitroimidazole derivatives, structurally related to secnidazole; significance unclear . Dysen Forte Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.
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