Noclot-Ea Tablets SpecificationRequires Prescription (YES/NO)YesGenericsAspirin, ClopidogrelUsed ForStrokeHow it worksClopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. Aspirin inhibits prostaglandin synthesis resulting in inhibition of platelet aggregation for their lifespan of about 7-10 days. The acetyl group of aspirin binds with a serine residue of cyclooxygenase-1 (COX-1), resulting in irreversible inactivation of the enzyme. Inhibition of COX-1 prevents conversion of arachidonic acid to thromboxane A2 (TXA2), which is a potent agonist of platelet aggregation.Noclot-Ea Tablets Usage And SafetyDosageAspirin, ClopidogrelSide EffectsUncommon: Thrombocytopenia, leucopenia, eosinophiliaRare: Neutropenia, including severe neutropeniaVery rare: Thrombotic thrombocytopenic purpura (TTP), aplastic anaemia, pancytopenia, agranulocytosis, severe thrombocytopenia, acquired haemophilia A, granulocytopenia, anaemiaDrug InteractionsOral anticoagulants , Heparin , Thrombolytics , NSAIDs , SSRIs . Clopidogrel : Inducers of CYP2C19 , Inhibitors of CYP2C19 , Proton Pump Inhibitors (PPI) , Anti-retroviral therapies (ART) . Aspirin : Uricosurics (benzbromarone, probenecid, sulfinpyrazone) , Methotrexate , Tenofovir , Valproic acid , Alcohol.IndicationIt is indicated for the prevention of ischemic events, myocardial infarction, stroke and cardiovascular death in patients with Acute Coronary Syndrome (ACS).When not to UseDue to the presence of both components of the medicinal product, Clopidogrel/Aspirin is contraindicated in case of:? Hypersensitivity to the active substances or to any of the excipients.? Severe hepatic impairment.? Active pathological bleeding such as peptic ulcer or intracranial haemorrhageNoclot-Ea Tablets PrecautionsPrecautionDue to the risk of bleeding and haematological adverse reactions, blood cell count determination and/or other appropriate testing should be promptly considered whenever clinical symptoms suggestive of bleeding arise during the course of treatment.Noclot-Ea Tablets WarningsWarning 1Patients should be followed carefully for any signs of bleeding including occult bleeding, especially during the first weeks of treatment and/or after invasive cardiac procedures or surgery. The concomitant administration of Clopidogrel/Aspirin with oral anticoagulants is not recommended since it may increase the intensity of bleeding.Warning 2Acquired haemophilia has been reported following use of clopidogrel. In cases of confirmed isolated activated Partial Thromboplastin Time (aPTT) prolongation with or without bleeding, acquired haemophilia should be considered. Patients with a confirmed diagnosis of acquired haemophilia should be managed and treated by specialists, and clopidogrel should be discontinued.Warning 3In patients with recent transient ischaemic attack or stroke who are at high risk of recurrent ischaemic events, the combination of ASA and clopidogrel has been shown to increase major bleeding. Therefore, such addition should be undertaken with caution outside of clinical situations where the combination has proven to be beneficial.Noclot-Ea Tablets Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.
Nocof drops are a medication that contains pseudoephedrine hydrochloride and dextromethorphan hydrobromide as active ingredients. They are used to relieve cough and nasal congestion caused by colds, allergies, or sinusitis. They are given by mouth as drops.
Noctamid Tablets SpecificationRequires Prescription (YES/NO)YesGenericsLormetazepamUsed ForInsomniaHow it worksIt contains the active ingredient lormetazepam, and belongs to the group of medicines called benzodiazepines. Benzodiazepines increase the action of GABA (a chemical messenger), which helps calm the brain down. This results in promotion of sleep . Noctamid Tablets Usage And SafetyDosageLormetazepamSide EffectsVery common (may affect more than 1 user in 10): ? headache. Common (may affect 1 to 10 users in 100): ? rapid swelling of the skin or the lining of the mouth and throat which can lead to obstruction of your airways (angioedema) ? feeling anxious ? reduced sex drive ? dizziness, sedation, sleepiness, reduced attention, loss of memory (amnesia), problems with your sight or speech, an unusual sense of taste (dysgeusia), slowed thinking ? fast heart rate ? vomiting, feeling sick (nausea), upper stomach pain, constipation, dry mouth ? itching (pruritis) ? difficulty passing urine ? reduced vitality (asthenia)Drug Interactions ? Medicines used to treat mental illness, depression, anxiety and mood disorders ? Medicines which make you drowsy or tired ? Strong painkillers and anaesthetics ? Medicines used to treat epilepsy ? Medicines for allergies that can cause drowsiness (e.g. antihistamines or cold medication) ? Medicines used for congestive heart failure (e.g. digoxin) and arrhythmia (irregular heartbeat) (e.g. beta-blockers) ? Medicines used for chronic bronchitis or asthma (e.g. theophylline, xanthine) ? Oestrogen-containing medicines ? Rifampicin, a medicine used to treat tuberculosis and other serious infections .IndicationIt is used to treat sleeping problems; this includes difficulty in falling asleep.When not to UseDo not take if: You have an allergy to lormetazepam, the active ingredient ; or any other benzodiazepines ? You have an allergy to any of the ingredients listed at the end of this leaflet ? You suffer from myasthenia gravis (a condition in which the muscles become weak and tire easily).Noctamid Tablets PrecautionsPrecautionIt may cause a short term loss of memory (anterograde amnesia). This occurs most often in the first few hours after taking the medicine. Make sure that you will be able to sleep without interruption for at least 7-8 hours in order to reduce this risk.Noctamid Tablets WarningsWarning 1Talk to your doctor before using Lormetazepam if you have severe breathing or chest problems . Warning 2Talk to your doctor before using Lormetazepam if you suffer from sleep apnoea (breathing problems when you are asleep) .Warning 3Talk to your doctor before using Lormetazepam tablets if you have myasthenia gravis (very weak or tired muscles) . Noctamid Tablets Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.
Noctamid Tablets 1mg 10X10's
Uses
It is used for Insomnia, Anxious mood
Side Effects
It can cause Excessive Sleeping
When not to use
Myasthenia gravis, hypersensitivity to benzodiazepines or to any of the excipients of Noctamid, severe respiratory insufficiency (e.g. severe chronic obstructive pulmonary disease) and sleep apnoea syndrome.
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Noclot-Ea Tablets SpecificationRequires Prescription (YES/NO)YesGenericsAspirin, ClopidogrelUsed ForStrokeHow it worksClopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on platelets. Aspirin inhibits prostaglandin synthesis resulting in inhibition of platelet aggregation for their lifespan of about 7-10 days. The acetyl group of aspirin binds with a serine residue of cyclooxygenase-1 (COX-1), resulting in irreversible inactivation of the enzyme. Inhibition of COX-1 prevents conversion of arachidonic acid to thromboxane A2 (TXA2), which is a potent agonist of platelet aggregation.Noclot-Ea Tablets Usage And SafetyDosageAspirin, ClopidogrelSide EffectsUncommon: Thrombocytopenia, leucopenia, eosinophiliaRare: Neutropenia, including severe neutropeniaVery rare: Thrombotic thrombocytopenic purpura (TTP), aplastic anaemia, pancytopenia, agranulocytosis, severe thrombocytopenia, acquired haemophilia A, granulocytopenia, anaemiaDrug InteractionsOral anticoagulants , Heparin , Thrombolytics , NSAIDs , SSRIs . Clopidogrel : Inducers of CYP2C19 , Inhibitors of CYP2C19 , Proton Pump Inhibitors (PPI) , Anti-retroviral therapies (ART) . Aspirin : Uricosurics (benzbromarone, probenecid, sulfinpyrazone) , Methotrexate , Tenofovir , Valproic acid , Alcohol.IndicationIt is indicated for the prevention of ischemic events, myocardial infarction, stroke and cardiovascular death in patients with Acute Coronary Syndrome (ACS).When not to UseDue to the presence of both components of the medicinal product, Clopidogrel/Aspirin is contraindicated in case of:? Hypersensitivity to the active substances or to any of the excipients.? Severe hepatic impairment.? Active pathological bleeding such as peptic ulcer or intracranial haemorrhageNoclot-Ea Tablets PrecautionsPrecautionDue to the risk of bleeding and haematological adverse reactions, blood cell count determination and/or other appropriate testing should be promptly considered whenever clinical symptoms suggestive of bleeding arise during the course of treatment.Noclot-Ea Tablets WarningsWarning 1Patients should be followed carefully for any signs of bleeding including occult bleeding, especially during the first weeks of treatment and/or after invasive cardiac procedures or surgery. The concomitant administration of Clopidogrel/Aspirin with oral anticoagulants is not recommended since it may increase the intensity of bleeding.Warning 2Acquired haemophilia has been reported following use of clopidogrel. In cases of confirmed isolated activated Partial Thromboplastin Time (aPTT) prolongation with or without bleeding, acquired haemophilia should be considered. Patients with a confirmed diagnosis of acquired haemophilia should be managed and treated by specialists, and clopidogrel should be discontinued.Warning 3In patients with recent transient ischaemic attack or stroke who are at high risk of recurrent ischaemic events, the combination of ASA and clopidogrel has been shown to increase major bleeding. Therefore, such addition should be undertaken with caution outside of clinical situations where the combination has proven to be beneficial.Noclot-Ea Tablets Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.
Nocof drops are a medication that contains pseudoephedrine hydrochloride and dextromethorphan hydrobromide as active ingredients. They are used to relieve cough and nasal congestion caused by colds, allergies, or sinusitis. They are given by mouth as drops.
NOCON Drops 15ml
NOCON Syrup 60ml
Noctamid Tablets 1mg 10X10's Uses It is used for Insomnia, Anxious mood Side Effects It can cause Excessive Sleeping When not to use Myasthenia gravis, hypersensitivity to benzodiazepines or to any of the excipients of Noctamid, severe respiratory insufficiency (e.g. severe chronic obstructive pulmonary disease) and sleep apnoea syndrome.
