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Ovasif Sachet SpecificationRequires Prescription (YES/NO)YesGenericsMyo-Inositol, QuatrefolicUsed ForPolycystic Ovary SyndromeHow it worksMyo Inositol (MI) administration has been reported to exert beneficial effects at metabolic, hormonal and ovarian level. MI displays specific effects on ovary, chiefly by modulating glucose metabolism and FSH-signaling. Moreover, MI may also improve ovarian functions by modulating steroid metabolism through non-insulin-dependent pathways. DCI contributes in mediating insulin activity mainly on non-ovarian tissues. Myo Inositol produces second messengers for FSH and glucose uptake, while D-chiroinositol provides second messengers promoting glucose uptake and glycogen synthesis. As DCI and MI activity likely involves different biological mechanisms, both inositol isoforms have been synergistically integrated according to a multi-targeted design, by combining MI and DCI. In addition to inositol components (MI/DCI); use of folate in expecting or pregnant females lowers the risk of recurrent spontaneous early pregnancy losses. Elevated homocysteine and reduced serum folate concentrations are risk factors for spontaneous abortions. Folate supplementation is expected to be beneficial in women with histories of early pregnancy loss. It also reduces homocysteine levels thereby improving pregnancy outcomes.Ovasif Sachet Usage And SafetyDosageMyo-Inositol, QuatrefolicSide EffectsGenerally, myo-inositol is well tolerated but may cause low blood sugar, especially if taking medications or other supplements that lower blood sugar. Nausea, fatigue, headache and dizziness may also occur. Folate supplements may cause anorexia, nausea, abdominal distension and flatulence. Certain Immune system disorders such as allergic reactions, comprising erythema, rash, pruritus, urticaria, dyspnea, and anaphylactic reactions (including shock) have also been reported. Frequency is not known.Drug InteractionsMyo Inositol :Calcium ? Iron ? Magnesium ? Zinc . Folate: Folate may interfere with the efficacy of antiepileptic medications such as phenytoin, fosphenytoin, phenobarbital, primidone. It may also decrease the effectiveness of pyrimethamine and sulfasalazine. IndicationIt is used to treat : ? Polycystic ovarian syndrome. ? Hyperandrogenism (Excess androgen production) ? Menstrual cycle disorders (such as Irregular periods)When not to UseHypersensitivity to inositol & folic acid/folate . Ovasif Sachet PrecautionsPrecautionInositol strongly binds divalent minerals such as magnesium, iron, calcium, and zinc. Inositol supplements should be taken apart from dietary products and aforementioned mineral supplements.Ovasif Sachet WarningsWarning 1Folic acid supplements might make seizures worse in people with seizure disorders, particularly in high doses . Warning 2Folic acid supplementation can sometimes mask the symptoms of serious and dangerous deficiency of vitamin B12.Warning 3Folate containing supplements should be used with caution in patients who have folate dependent tumors . Ovasif Sachet Additional InformationPregnancy categoryAlways consult your physician before using any medicine.Storage (YES/NO)Store this medicine at room temperature, away from direct light and heat.

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