AKNEGATE CN Gel 20gm Allschoolabs -

Description

INTRODUCTION
AKNEGATE CN GEL is a combination of Clindamycin and Nicotinamide which belongs to a group of medicines called Lincomycin antibiotics and Vitamin B3 complex, respectively.?AKNEGATE CN GEL is used to treat mild to moderate acne which is a skin condition that occurs when hair follicles become plugged with oil and dead skin cells which may occur due to variety of causes such as genetics, fluctuating hormone levels, stress, high humidity or using oily or greasy personal care products which may affect people of all ages.
It is characterized by symptoms such as open or closed plugged pores, small red & tender bumps, pimples, large, solid?or painful lumps under the skin?and painful & pus-filled lumps under the skin.
Before using AKNEGATE CN GEL inform your doctor if you have liver, kidney, lung or heart diseases. Avoid applying AKNEGATE CN GEL to a cut, scrapped, sunburnt or eczema affected skin.
AKNEGATE CN GEL should be used with caution in pregnant and in breastfeeding women. AKNEGATE CN GEL is not recommended for use in children and adolescents (below 12 years). Consult your doctor before applying.
The most common side effects of using AKNEGATE CN GEL are skin inflammation, contact dermatitis (red, itchy rash), inflammation of hair follicles, itchy skin, dry skin?and peeling of skin. Consult your doctor if any of these symptoms worsen.
USES OF AKNEGATE CN GEL

Treats mild to moderate acne

HOW AKNEGATE CN GEL WORKS
AKNEGATE CN GEL helps to treat acne, where Clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes), a bacteria found in sebaceous glands and follicles?and Nicotinamide exerts anti-inflammatory effect in acne and interrupts sebum production.
DIRECTIONS FOR USE
Apply AKNEGATE CN GEL as advised by your physician. It is for external use only. Before applying the medicine normally wash and dry the affected area and apply a thin layer of this medicine on the affected area. Treated areas on the face need not be covered with a plaster or bandage. Do not apply this medicine beyond the recommended duration. Avoid applying AKNEGATE CN GEL around your eyes, including eyelids. Rinse it off with water if you accidentally get it in these areas.
SIDE EFFECTS OF AKNEGATE CN GEL

COMMON

Contact dermatitis (red, itchy rash)

Inflammation of hair follicles

Itchy skin

Dry skin

Peeling of skin

HOW TO MANAGE SIDE EFFECTS
Skin rash/Itchy skin:
Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin and apply calamine lotion as a coolant. Discuss with your doctor if the symptom worsens.
WARNING & PRECAUTIONS

PREGNANCY
AKNEGATE CN GEL should be used with caution in pregnant women. Consult your doctor before applying.
BREASTFEEDING
AKNEGATE CN GEL should be used with caution in breastfeeding women. Consult your doctor before applying.
ALLERGY
AKNEGATE CN GEL is not recommended for use if you are allergic to Clindamycin, Nicotinamide?or any other ingredients of this medicine.
OTHERS
AKNEGATE CN GEL is not recommended for use if you have:
Eczema (skin inflammation)

Cut, scrapped, sunburnt skin
Use in Pediatrics:
AKNEGATE CN GEL is not recommended for use in children and adolescents (below 12 years). Consult your doctor before using it for your child.
Use in Geriatrics:
There is no information on the use of AKNEGATE CN GEL in elderly patients. Consult with your doctor before using.
INTERACTIONS
A. Drug ? Drug interactions:
Before using AKNEGATE CN GEL, inform your doctor if you are taking any of the following medicines:
Acepromazine (used a sedative/tranquilizer)

Acetaminophen (used to treat pain and inflammation)
Overdosage:
If you or anyone else accidentally ingests or applies too much of AKNEGATE CN GEL, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS

Drug :?? Clindamycin, Nicotinamide

Pharmacological Category :?? Lincomycin antibiotics, Vitamin B3 complex

Therapeutic Indication :?? Mild to moderate acne

Dosage Forms :?? Gel, Cream, Ointment

MORE INFORMATION

Keep AKNEGATE CN GEL out of reach of children

Store AKNEGATE CN GEL at a temperature below 25?C

FAQs ABOUT AKNEGATE CN GEL
What special precautions should I follow while using AKNEGATE CN GEL?
Before using AKNEGATE CN GEL inform your doctor if you have liver, kidney, lung or heart diseases. Avoid applying AKNEGATE CN GEL to a cut, scrapped, sunburnt or eczema affected skin. This medicine is not for oral, ophthalmic or intravaginal use.
What is AKNEGATE CN GEL used for?
AKNEGATE CN GEL is indicated for the treatment of mild to moderate acne in patients above 12 years of age. Do not use it for any other condition other than that prescribed by your doctor.
How should I use AKNEGATE CN GEL?
Always apply AKNEGATE CN GEL, as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. Treated areas on the face need not be covered with a plaster or bandage. Do not apply this medicine on your face beyond 5 days. Avoid applying AKNEGATE CN GEL around your eyes, including eyelids.
Is AKNEGATE CN GEL safe to use in pregnant and breastfeeding women?
AKNEGATE CN GEL should be used with caution during pregnancy, women planning for pregnancy and in breastfeeding women. Consult your doctor before applying.
Can AKNEGATE CN GEL cause skin irritation or itchy skin?
AKNEGATE CN GEL may cause skin irritation or itchy skin. Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin and apply calamine lotion as a coolant. Discuss with your doctor if the symptom worsens.
REFERENCES
1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide & Other Antibacterial Antibiotics; Urinary Antiseptics and Vitamins. Essentials of medical pharmacology. Seventh edition. 2013. Page ? 756 & 914.
2. Pooja Bains, Manpreet Kaur, Jasleen Kaur, Saurabh Sharma. Nicotinamide: Mechanism of action and indications in dermatology. Indian Journal of Dermatology, Venereology?and Leprology. 2018. [Accessed on 7th June 2022]?https://ijdvl.com/nicotinamide-mechanism-of-action-and-indications-in-dermatology/
3. A R Shalita, J G Smith, L C Parish, M S Sofman, D K Chalker. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. June 1995. [Accessed on 7th June 2022]?https://pubmed.ncbi.nlm.nih.gov/7657446/
4. Curatio. Clinmiskin Gel. [Accessed on 7th June 2022]?https://curatiohealthcare.com/product/clinmiskin-gel/
5. Bionova. Clindis N Acne Gel (Clindamycin Nicotinamide). [Accessed on 7th June 2022]?https://www.bionova.co.in/clindis-anti-acne-gel.html
6. Leeford Healthcare. Clinsol Gel (Clindamycin Nicotinamide). [Accessed on 7th June 2022]?https://www.leeford.in/product/1164/clinsol-gel
7. Aliana Pharma. Clindasoft Gel (Clindamycin Nicotinamide). [Accessed on 7th June 2022]?https://alainapharma.com/Clindamycin and Nicotinamide Gel.html
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