Amoxicillin is indicated for the treatment of bacterial infections caused by amoxicillin-sensitive gram-positive and gram-negative pathogens. This could include;

Infections of the upper respiratory tract, including infections of the ears, nose and throat: Acute otitis media, acute sinusitis and bacterial pharyngitis
Infections of the lower respiratory tract: Acute exacerbation of chronic bronchitis, community-acquired pneumonia
Infections of the lower urinary tract: Cystitis
Prophylaxis of endocarditis in patients at risk i.e. surgery in the oral cavity or upper airways
Consideration should be given to official guidance on the appropriate use of antibacterial agents
Susceptibility of the causative organism to the treatment should be tested (if possible), although therapy may be initiated before the results are available.