Anafril tablet 25 mg 2_10?s works by restoring the balance of certain natural substances (serotonin, among others) in the brain.
Side effects
Major & minor side effects for Anafril tablet 25 mg 2_10?s

Dizziness severe

Irritability severe

Blurred vision severe

Dry mouth severe

Nausea or Vomiting severe

Swelling of face and feet severe

Acid or sour stomach

Constipation

Shaking of hands or feet

Mouth ulcers

Irregular menstrual periods

Uses of Anafril tablet 25 mg 2_10?s
What is it prescribed for?

Obsessive Compulsive Disorder
Anafril tablet 25 mg 2_10?s is used in the treatment of the obsessive-compulsive disorder which is a brain disorder characterized by repetitive thoughts and behaviour.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed in 2 to 6 hours.

Duration of Effect
The effect of this medicine lasts for an average duration of 4 hours and 7 to 8 hours for an active metabolite.

Safe with Alchohol?
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating heavy machinery.

Is it habit forming?
No habit forming tendency has been reported

Usage in pregnancy?
This medicine is not recommended for use in pregnant women.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women.

When not to use?

Allergy
Not recommended in patients with known allergy to Anafril tablet 25 mg 2_10?s or other tricyclic antidepressants.

Monoamine oxidase inhibitors (MAOI)
Anafril tablet 25 mg 2_10?s is not recommended in patients who have taken Monoamine oxidase inhibitors within the last 14 days.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women.

Breast-feeding
This medicine is not recommended for use in breastfeeding women.

General Warnings

Suicidal thoughts
Use with caution in the patients with major depressive disorder due to the increased risk of suicidal thoughts. Close monitoring of these symptoms is necessary. Inform the doctor if these symptoms worsen.

Serotonin Syndrome
This medicine may cause potentially life-threatening serotonin syndrome. Immediate medical treatment should be initiated if any symptoms of agitation, hallucinations, dizziness, tremor, seizures, nausea, and vomiting appear.

Effect on heart
This medicine may lower the blood pressure, therefore should be used with caution in patients with heart diseases. Close monitoring of blood pressure is necessary. Inform the doctor if any symptoms such as dizziness, lightheadedness appear.

Impaired liver function
This medicine may increase the levels of liver enzymes like AST and ALT. Periodic monitoring of liver parameters is necessary. Lower or less frequent dosing is preferred in the patients with severe liver injury.

Body weight
This medicine may either cause weight loss or weight gain. Inform the doctor if you experience any changes in the body weight.

Withdrawal Symptoms
Do not stop taking this medicine suddenly as it may cause withdrawal symptoms like nausea, headache, anxiety, dizziness, and irritability. Gradual dose reduction should be made under the doctor’s supervision.

Pediatric population
This medicine is not recommended for children under the age of 10 years.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it?s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose. Schedule H

Interactions
Interaction with Medicines

Tramadol severe

Antihypertensives moderate

Monoamine oxidase inhibitors severe

Disease interactions

severe
Use with caution the patients suffering from depression and other psychiatric disorders due to the increased risk of suicidal thoughts especially at the beginning of the treatment and at the time of dose change. Discontinue the medicine and inform the doctor if these symptoms appear.

severe
Anafril tablet 25 mg 2_10?s may increase the risk of seizures. Inform the doctor if you have any history of seizures or any head injury. The dose of this medicine should be adjusted based on the clinical condition.

General Instructions

Take Anafril tablet 25 mg 2_10?s as instructed by your doctor. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause withdrawal symptoms.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

References

webmd.com –
Clomipramine [Internet].
Available from: https://www.webmd.com/drugs/2/drug-1305/clomipramine-oral/details
[cited 6/7/2020].