Uses & Effectiveness Overview Angel?s trumpet is a plant. The leaves and flowers are used to make medicine. Despite serious safety concerns, people use angel?s trumpet as a recreational drug to induce hallucinations and euphoria. It is also used for asthma and other conditions, but there is no good scientific evidence to support these uses. Vitamin B6, also known as pyridoxine, plays a crucial role in brain development and function. It is involved in synthesizing neurotransmitters like serotonin and dopamine, which regulate mood, sleep, and behavior, making it an essential nutrient for maintaining mental well-being. Side Effects When taken by mouth: Angel?s trumpet is UNSAFE. The entire plant is poisonous, but the leaves and seeds contain the most poison. Taking angel?s trumpet can cause confusion, dilated pupils, intense thirst, dry skin, flushing, fever, high or low blood pressure, fast heartbeat, difficulty breathing, hallucinations, nervousness, loss of memory, convulsions, paralysis, coma, and death. Interactions Moderate Interaction Be cautious with this combination Drying medications (Anticholinergic drugs) interacts with ANGEL?S TRUMPET Angel?s trumpet contains chemicals that cause a drying effect. It also affects the brain and heart. Drying medications called anticholinergic drugs can also cause these effects. Taking angel?s trumpet and drying medications together might cause side effects including dry skin, dizziness, low blood pressure, fast heartbeat, and other serious side effects. Some of these drying medications include atropine, scopolamine, and some medications used for allergies (antihistamines), and for depression (antidepressants). Special Precautionsand Warnings When taken by mouth: Angel?s trumpet is UNSAFE. The entire plant is poisonous, but the leaves and seeds contain the most poison. Taking angel?s trumpet can cause confusion, dilated pupils, intense thirst, dry skin, flushing, fever, high or low blood pressure, fast heartbeat, difficulty breathing, hallucinations, nervousness, loss of memory, convulsions, paralysis, coma, and death. It is UNSAFE for anyone to use angel?s trumpet. But angel?s trumpet is especially dangerous for people with the following conditions: Pregnancy and breast-feeding: Angel?s trumpet is UNSAFE when taken by mouth. The entire plant is considered poisonous. Don?t use it. Children: Angel?s trumpet is UNSAFE when taken by mouth. Severe poisoning has occurred in children who ate angel?s trumpet accidentally and in teenagers who used angel?s trumpet as a recreational drug. Heart failure and fluid build up in the body (congestive heart failure or CHF): Angel?s trumpet might cause rapid heartbeat and make CHF worse. Don?t use it. Constipation: Angel?s trumpet might make constipation worse. Don?t use it. Down syndrome: People with Down syndrome might be especially sensitive to the dangerous side effects of angel?s trumpet. Don?t use it. Persistent heartburn: Persistent heartburn (gastroesophageal reflux disease or GERD) is a condition in which stomach juices back up into the tube that connects the mouth and the stomach (esophagus). Angel?s trumpet might make this condition worse because it can delay stomach emptying. Don?t use it. Fever: Angel?s trumpet might make fever worse. Don?t use it. Stomach ulcer: Angel?s trumpet might delay stomach emptying and make stomach ulcers worse. Don?t use it. A group of eye disorders that can lead to vision loss (glaucoma): Angel?s trumpet might raise the pressure inside the eye. This could make narrow-angle glaucoma worse. Don?t use it. Conditions that block the gastrointestinal tract such as atony, paralytic ileus, and stenosis: Angel?s trumpet might make these conditions worse. Don?t use it. Rapid heartbeat (tachycardia): Angel?s trumpet might cause make tachycardia worse. Don?t use it. A type of inflammatory bowel disease (ulcerative colitis): Angel?s trumpet might make this condition worse. Don?t use it. Difficult urination: Angel?s trumpet might make this condition worse. Don?t use it. Dosing The appropriate dose of angel?s trumpet depends on several factors such as the user?s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for angel?s trumpet. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.