Anofer S 100mg Injection 5ml Allschoolabs -

Description

INTRODUCTION
ANOFER S 100MG contains Iron sucrose which belongs to the group of medicines called hematinic. It is indicated in the treatment of iron deficiency anemia in both adults and in children (above 2 years) with chronic kidney disease. It is preferably used in patients who have intolerance or unsatisfactory response to oral iron. Iron deficiency anemia is a condition in which the body lacks enough amount of mineral ion ?iron? which is responsible for the formation of healthy red blood cells and oxygen transport in the body.
Systemic administration of iron sucrose effectively replenishes and restores iron in the body. It helps in the formation of healthy red blood cells and transport of oxygen, leading to the correction of anemia caused by iron deficiency. Along with the treatment, eating a well-balanced diet including lots of green leafy vegetables, dry fruits, meat, beets, pomegranate, beans etc. can also help you to achieve better results.
This medicine is not meant for self-administration. Your doctor or nurse will administer it into your vein as an injection or infusion. If required, it can be given along with dialysis by putting in the venous line. The most common side effects of this medicine are injection site pain, itching, irritation, redness or leakage, metallic taste and nausea. These are usually temporary and wears off after some time. However, if it bothers you, inform your doctor.
It will be given to you only by a doctor or nurse into the vein (intravenously) either as a slow injection or as an infusion drip. Before taking this medicine, inform your doctor if you have an iron-overload disorder, iron-independent anemia or liver disease. Ask your doctor for advice before taking this medicine, if you are pregnant or breast-feeding. It is strictly not recommended for use in children under 18 years due to lack of data on dosing. Consult your doctor before taking.
USES OF ANOFER S 100MG

Treats iron deficiency anemia in both adults and in children (above 2 years) with chronic kidney disease who are intolerant or unresponsive to oral iron therapy

HOW ANOFER S 100MG WORKS
Following systemic administration, iron sucrose dissociates into iron and sucrose inside the body. The dissociated iron forms a complex with a plasma protein called transferrin?and is transported into the target cells. This iron is further incorporated into hemoglobin as the cells mature into red blood cells and transports healthy red blood cells and oxygen within the body.
DIRECTIONS FOR USE
ANOFER S 100MG will be given to you only by a doctor or nurse into the vein (intravenously) either as a slow injection or as an infusion drip. It can also be administered during dialysis if applicable. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
SIDE EFFECTS OF ANOFER S 100MG

SERIOUS

Severe allergic reactions (such as feeling dizzy or faint, light-headedness, low blood pressure, swelling of the face, difficulty in breathing and chest pain)

COMMON

Injection site reactions (such as pain, irritation, itching, redness or leakage at injected site)

Metallic taste

High or low blood pressure

Feeling sick (nausea)

RARE

Drowsiness

Palpitations (irregular heartbeat)

Changes in the color of the urine

Chest pain

Increased sweating

Fever

HOW TO MANAGE SIDE EFFECTS
Feeling sick (nausea):
Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.
WARNING & PRECAUTIONS

PREGNANCY
ANOFER S 100MG should be used with caution in pregnant women. Consult your doctor before taking.
BREASTFEEDING
ANOFER S 100MG should be used with caution in breastfeeding women. Consult your doctor before taking.
DRIVING AND USING MACHINES
Do not drive or operate any machines because this medicine may cause dizziness, confusion or light-headedness.
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
LIVER
ANOFER S 100MG should be taken with caution in patients with liver disease. Consult your doctor for advice.
ALLERGY
Do not take this medicine if you are allergic to iron sucrose or other injectable preparations.
OTHERS
Before taking this medicine, inform your doctor if you have:
A history of medicine allergy

Systemic lupus erythematosus (an allergic skin reaction)

Rheumatoid arthritis (joint pain)

Eczema or other allergies

An infection

INTERACTIONS
Talk to your doctor, if you are taking,
Oral iron preparations (e.g. ferrous ascorbate, ferrous sulphate, ferric citrate)

SYNOPSIS

Drug :?? Iron sucrose

Pharmacological Category :?? Hematinics, Anti-anemic agent

Therapeutic Indication :?? Iron deficiency anemia

Dosage Forms :?? Injection

MORE INFORMATION
Store below 20-25?C and keep out of reach of children.
FAQs ABOUT ANOFER S 100MG
Can ANOFER S 100MG be given intramuscularly (i.m.)?
It will be given to you only by a doctor or nurse into the vein (intravenously) either as a slow injection or as an infusion drip. It can also be administered during dialysis if applicable.
Can ANOFER S 100MG be given to children?
Yes. It is applicable for use in children (above 2 years) with chronic kidney disease. However, use in children below 2 years of age is not recommended.
How long should I take ANOFER S 100MG to achieve better results?
The duration of the therapy differs from person to person depending upon their age and severity of the disease. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
REFERENCES
1. Kenneth Kaushansky and Thomas J. Kipps. Hematopoietic Agents: Growth factor, Minerals and Vitamins. Goodman & Gilman?s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page ?1085.
2. American Regent, Inc. Safety and Efficacy of Iron Sucrose in Children. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on February 2018] [Accessed 22nd December 2020]?https://clinicaltrials.gov/ct2/show/NCT00239642
3. Shelley E. Crary,?Katherine Hall?and?George R. Buchanan. Intravenous Iron Sucrose for Children with Iron Deficiency Failing to Respond to Oral Iron Therapy. NCBI; PMC US National Library of Medicine, National Institute of Health. December 2010. [Accessed 22nd December 2020]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079959/
4. Alka Kriplani,?Reeta Mahey,?Biswa Bhusan Dash,?Vidushi Kulshreshta,?Nutan Agarwal,?and?Neerja Bhatla. Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy. NCBI; PMC US National Library of Medicine, National Institute of Health. July 2013. [Accessed 22nd December 2020]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767254/
5. Elpis Mantadakis,?Emmanouela Tsouvala,?Varvara Xanthopoulou,?Athanassios Chatzimichael. Intravenous iron sucrose for children with iron deficiency anemia: a single institution study. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. February 2016. [Accessed 22nd December 2020]?https://pubmed.ncbi.nlm.nih.gov/25754747/
6.?Vifor France. Electronic Medicines Compendium (EMC); [Revised on October 2020] [Accessed 22nd December 2020]?https://www.medicines.org.uk/emc/files/pil.5911.pdf
7. Vifor (International) Inc. U.S. Food & Drug Administration. [Revised on November 2017] [Accessed 22nd December 2020].?https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021135s032lbl.pdf
8. Vifor (International) Inc., Switzerland. Venofer iron sucrose injection, USP. Venofer.com. [Revised on September 2020] [Accessed 22nd December 2020]?https://www.venofer.com/dosing https://www.venofer.com/pdfs/venofer-prescribing-information.pdf
USEFUL DIAGNOSTIC TESTS