Benipro tablet 500 mg 20?s lowers high levels of uric acid in your body by helping the kidneys to get rid of uric acid.
Side effects
Major & minor side effects for Benipro tablet 500 mg 20?s

Headache

Loss of appetite

Nausea and vomiting

Dizziness

Difficult or painful urination

Pain in the lower back and side

Skin Rash

Cough rare

Fever rare

Weight gain rare

Unusual tiredness or weakness rare

Irregular breathing rare

Uses of Benipro tablet 500 mg 20?s
What is it prescribed for?

Gouty arthritis
This medicine is used in the treatment of gout and gouty arthritis, a type of arthritis resulting due to the deposition of excess uric acid crystals in the joints characterized by severe pain, redness, and swelling in the joints, especially on the big toes.

Adjunct to antibiotic therapy
This medicine is used as an adjunct to antibiotic therapy to make them more effective

Concerns

Frequently asked questions

Onset of action
The amount of time required for this medicine to show its action is not clinically established.

Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Benipro tablet 500 mg 20?s or any other inactive ingredients present along with it.

Blood Dyscrasias
This medicine is not recommended for use in patients with blood disorders due to the risk of worsening of the patient’s condition.

Severe renal impairment
This medicine is not recommended for use in patients with severe kidney insufficiency (CrCl below 30 mL/min) due to the risk of worsening of the patient’s condition.

Uric acid kidney stonesk
This medicine is not recommended for use in patients with uric acid kidney stones due to the risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

General Warnings

Kidney impairment
This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe kidney insufficiency (CrCl below 30 mL/min).

Hydration
Drink adequate amount of water (2 liters/day) to increase the urine output and to prevent the formation of kidney stones.

Allergic reactions
This medicine may cause severe allergic reactions such as skin rash, swelling of lips or face, etc. in some patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery
This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Athletes
S5 – Diuretics and Other Masking Agents Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Glucose-6-phosphate-dehydrogenase (G6PD) deficiency
This medicine should be used with caution in patients with G6PD deficiency due to the increased risk of worsening of the patient’s condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children
This medicine is not recommended for use in children below 18 years of age for the treatment of gout and children below 2 years of age as an adjunct to antibiotic therapy.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Dapsone moderate

Ganciclovir moderate

Zidovudine moderate

Glimepiride moderate

Methotrexate severe

Tazobactam moderate

Disease interactions

moderate
This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe kidney insufficiency (CrCl below 30 mL/min)

moderate
This medicine should be used with caution in patients with peptic ulcer disease due to the increased risk of worsening of the patient’s condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

Take this medicine exactly as advised by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Drink adequate amount of water to prevent the formation of kidney stones. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.

Other details

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

References

webmd.com –
Probenecid [Internet].
Available from: https://www.webmd.com/drugs/2/drug-8697/probenecid-oral/details
[cited 11/9/2020].