Uses & Effectiveness We currently have no information for CANNABINOL (CBN) overview. Overview Cannabinol is a chemical found in the Cannabis sativa plant. Research on this chemical is limited and its effects are unclear. Some early research suggests that cannabinol might affect the immune system and reduce pain. There is interest in using cannabinol for sleep, pain, and as an appetite stimulant. Cannabinol (CBN) is a unique cannabinoid found in cannabis that is becoming increasingly popular for its sedative properties, making it a potential natural alternative to sleeping pills. Side Effects When taken by mouth: There isn?t enough reliable information to know if cannabinol is safe or what the side effects might be. Interactions Moderate Interaction Be cautious with this combination Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates) interacts with CANNABINOL (CBN) Some medications are changed and broken down by the liver. Cannabinol might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications. Medications that decrease breakdown of other medications by the liver (Cytochrome P450 2C9 (CYP2C9) inhibitors) interacts with CANNABINOL (CBN) Cannabinol is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down cannabinol. This could change the effects and side effects of cannabinol. Medications that decrease the breakdown of other medications in the liver (Cytochrome P450 3A4 (CYP3A4) inhibitors) interacts with CANNABINOL (CBN) Cannabinol is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down cannabinol. This could change the effects and side effects of cannabinol. Medications changed by the liver (Cytochrome P450 2B6 (CYP2B6) substrates) interacts with CANNABINOL (CBN) Some medications are changed and broken down by the liver. Cannabinol might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications. Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CANNABINOL (CBN) Some medications are changed and broken down by the liver. Cannabinol might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications. Medications changed by the liver (Cytochrome P450 2E1 (CYP2E1) substrates) interacts with CANNABINOL (CBN) Some medications are changed and broken down by the liver. Cannabinol might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications. Special Precautionsand Warnings When taken by mouth: There isn?t enough reliable information to know if cannabinol is safe or what the side effects might be. Pregnancy and breast-feeding: There isn?t enough reliable information to know if cannabinol is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use. Dosing There isn?t enough reliable information to know what an appropriate dose of cannabinol might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.